The Correlation of initial hematological feature with advanced stage in Chronic Lymphocytic Leukemia in Kurdistan Region of Iraq

Background and objective: Chronic lymphocytic leukemia (CLL) is considered by an accumulation of matured lymphocytes in the blood, bone marrow, spleen. And lymph .We aimed to find the correlation of initial hematological feature with advanced stage in CLL. Methods: A retrospective study was conducte...

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Autor principal:	tavan Ismeil
Formato:	article
Lenguaje:	EN
Publicado:	Salahaddin University-Erbil 2021
Materias:	chronic lymphocytic leukemia; initial laboratory; advanced stage kri Technology T Science Q
Acceso en línea:	https://doaj.org/article/a8aabfbe1d3845d0ba842efc8985d9a5
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spelling	oai:doaj.org-article:a8aabfbe1d3845d0ba842efc8985d9a52021-11-07T06:31:30ZThe Correlation of initial hematological feature with advanced stage in Chronic Lymphocytic Leukemia in Kurdistan Region of Iraq10.21271/ZJPAS.33.5.122218-02302412-3986https://doaj.org/article/a8aabfbe1d3845d0ba842efc8985d9a52021-10-01T00:00:00Zhttps://zancojournals.su.edu.krd/index.php/JPAS/article/view/4097https://doaj.org/toc/2218-0230https://doaj.org/toc/2412-3986Background and objective: Chronic lymphocytic leukemia (CLL) is considered by an accumulation of matured lymphocytes in the blood, bone marrow, spleen. And lymph .We aimed to find the correlation of initial hematological feature with advanced stage in CLL. Methods: A retrospective study was conducted on 138 patients with CLL, confirmed by flow cytometry of peripheral blood collected in Hiwa Hematological and Oncological Hospital in Sulaimani, Nanakaly Hospital in Hawler, and Azadi Hematology - Oncology Center in Duhok, Kurdistan Region of Iraq dated from January 1, 2010, to December 31, 2020. Results: The mean age of 63.07±11 years with male predominance. The majority of patients at presentation were Rai Stage II and Binet stage A. The frequency of DAT positivity was found in (6.5%), which also established appositive relationship with advanced stage, there were statistically significant relation of hemoglobin level, platelet counts, LDH level to Rai stage and Binet stage disease (P value <0.001), No association were noted between different age groups and initial laboratory finding, also no relation of gender to staging. Conclusion: In the present study there was a significant relation between laboratory findings (hemoglobin, platelet count, LDH levels) to with staging, in addition DAT positivity demonstrated a significant correlation with advanced stage, those with High LDH levels associated with more advanced Rai stage.tavan IsmeilSalahaddin University-Erbilarticlechronic lymphocytic leukemia; initial laboratory; advanced stagekriTechnologyTScienceQENZanco Journal of Pure and Applied Sciences, Vol 33, Iss 5, Pp 105-115 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	chronic lymphocytic leukemia; initial laboratory; advanced stage kri Technology T Science Q
spellingShingle	chronic lymphocytic leukemia; initial laboratory; advanced stage kri Technology T Science Q tavan Ismeil The Correlation of initial hematological feature with advanced stage in Chronic Lymphocytic Leukemia in Kurdistan Region of Iraq
description	Background and objective: Chronic lymphocytic leukemia (CLL) is considered by an accumulation of matured lymphocytes in the blood, bone marrow, spleen. And lymph .We aimed to find the correlation of initial hematological feature with advanced stage in CLL. Methods: A retrospective study was conducted on 138 patients with CLL, confirmed by flow cytometry of peripheral blood collected in Hiwa Hematological and Oncological Hospital in Sulaimani, Nanakaly Hospital in Hawler, and Azadi Hematology - Oncology Center in Duhok, Kurdistan Region of Iraq dated from January 1, 2010, to December 31, 2020. Results: The mean age of 63.07±11 years with male predominance. The majority of patients at presentation were Rai Stage II and Binet stage A. The frequency of DAT positivity was found in (6.5%), which also established appositive relationship with advanced stage, there were statistically significant relation of hemoglobin level, platelet counts, LDH level to Rai stage and Binet stage disease (P value <0.001), No association were noted between different age groups and initial laboratory finding, also no relation of gender to staging. Conclusion: In the present study there was a significant relation between laboratory findings (hemoglobin, platelet count, LDH levels) to with staging, in addition DAT positivity demonstrated a significant correlation with advanced stage, those with High LDH levels associated with more advanced Rai stage.
format	article
author	tavan Ismeil
author_facet	tavan Ismeil
author_sort	tavan Ismeil
title	The Correlation of initial hematological feature with advanced stage in Chronic Lymphocytic Leukemia in Kurdistan Region of Iraq
title_short	The Correlation of initial hematological feature with advanced stage in Chronic Lymphocytic Leukemia in Kurdistan Region of Iraq
title_full	The Correlation of initial hematological feature with advanced stage in Chronic Lymphocytic Leukemia in Kurdistan Region of Iraq
title_fullStr	The Correlation of initial hematological feature with advanced stage in Chronic Lymphocytic Leukemia in Kurdistan Region of Iraq
title_full_unstemmed	The Correlation of initial hematological feature with advanced stage in Chronic Lymphocytic Leukemia in Kurdistan Region of Iraq
title_sort	correlation of initial hematological feature with advanced stage in chronic lymphocytic leukemia in kurdistan region of iraq
publisher	Salahaddin University-Erbil
publishDate	2021
url	https://doaj.org/article/a8aabfbe1d3845d0ba842efc8985d9a5
work_keys_str_mv	AT tavanismeil thecorrelationofinitialhematologicalfeaturewithadvancedstageinchroniclymphocyticleukemiainkurdistanregionofiraq AT tavanismeil correlationofinitialhematologicalfeaturewithadvancedstageinchroniclymphocyticleukemiainkurdistanregionofiraq
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The Correlation of initial hematological feature with advanced stage in Chronic Lymphocytic Leukemia in Kurdistan Region of Iraq

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