IMMUNOMODULATORY EFFECT OF SOTALOL HYDROHLORIDE UNDER ACUTE STRESS

It was established that acute stress in period induction of the local and systemic immune response to thymus-dependent antigen caused an inhibition of expression of delayed-type hypersensitivity reactions, did not effect on antibody production in the regional lymph node under the local response and...

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Autores principales:	D. Ju. Shilov, Ju. I. Shilov
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	stress adrenoceptors the immune response Science Q
Acceso en línea:	https://doaj.org/article/a8afcb0099db4448bf399136cc7c6c50
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spelling	oai:doaj.org-article:a8afcb0099db4448bf399136cc7c6c502021-11-23T06:14:20ZIMMUNOMODULATORY EFFECT OF SOTALOL HYDROHLORIDE UNDER ACUTE STRESS2541-94202587-9596https://doaj.org/article/a8afcb0099db4448bf399136cc7c6c502012-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/948https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596It was established that acute stress in period induction of the local and systemic immune response to thymus-dependent antigen caused an inhibition of expression of delayed-type hypersensitivity reactions, did not effect on antibody production in the regional lymph node under the local response and suppressed of antibody production in the spleen under the systemic immune response. Administration of sotalol hydrochloride (antagonist of beta-adrenoceptors with peripheral action) canceled these changes, that points to participate in their implementation of immunosuppressive signals from the peripheral beta-adrenergic receptors.D. Ju. ShilovJu. I. ShilovScientific Сentre for Family Health and Human Reproduction Problemsarticlestressadrenoceptorsthe immune responseScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3(2), Pp 337-342 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	stress adrenoceptors the immune response Science Q
spellingShingle	stress adrenoceptors the immune response Science Q D. Ju. Shilov Ju. I. Shilov IMMUNOMODULATORY EFFECT OF SOTALOL HYDROHLORIDE UNDER ACUTE STRESS
description	It was established that acute stress in period induction of the local and systemic immune response to thymus-dependent antigen caused an inhibition of expression of delayed-type hypersensitivity reactions, did not effect on antibody production in the regional lymph node under the local response and suppressed of antibody production in the spleen under the systemic immune response. Administration of sotalol hydrochloride (antagonist of beta-adrenoceptors with peripheral action) canceled these changes, that points to participate in their implementation of immunosuppressive signals from the peripheral beta-adrenergic receptors.
format	article
author	D. Ju. Shilov Ju. I. Shilov
author_facet	D. Ju. Shilov Ju. I. Shilov
author_sort	D. Ju. Shilov
title	IMMUNOMODULATORY EFFECT OF SOTALOL HYDROHLORIDE UNDER ACUTE STRESS
title_short	IMMUNOMODULATORY EFFECT OF SOTALOL HYDROHLORIDE UNDER ACUTE STRESS
title_full	IMMUNOMODULATORY EFFECT OF SOTALOL HYDROHLORIDE UNDER ACUTE STRESS
title_fullStr	IMMUNOMODULATORY EFFECT OF SOTALOL HYDROHLORIDE UNDER ACUTE STRESS
title_full_unstemmed	IMMUNOMODULATORY EFFECT OF SOTALOL HYDROHLORIDE UNDER ACUTE STRESS
title_sort	immunomodulatory effect of sotalol hydrohloride under acute stress
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/a8afcb0099db4448bf399136cc7c6c50
work_keys_str_mv	AT djushilov immunomodulatoryeffectofsotalolhydrohlorideunderacutestress AT juishilov immunomodulatoryeffectofsotalolhydrohlorideunderacutestress
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IMMUNOMODULATORY EFFECT OF SOTALOL HYDROHLORIDE UNDER ACUTE STRESS

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