Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter
Bacteria adapt their growth rate to their metabolic status and environmental conditions by modulating the length of their G1 period. Here the authors show that an increase in c-di-GMP concentration modulates the activity of kinase ShkA and transcription factor TacA, thus enabling G1/S transition in...
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Nature Portfolio
2020
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oai:doaj.org-article:a8b0383615d04194986ba09c5f07fc8e2021-12-02T14:41:24ZPrecise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter10.1038/s41467-020-14585-62041-1723https://doaj.org/article/a8b0383615d04194986ba09c5f07fc8e2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14585-6https://doaj.org/toc/2041-1723Bacteria adapt their growth rate to their metabolic status and environmental conditions by modulating the length of their G1 period. Here the authors show that an increase in c-di-GMP concentration modulates the activity of kinase ShkA and transcription factor TacA, thus enabling G1/S transition in Caulobacter.Andreas KaczmarczykAntje M. HempelChristoph von ArxRaphael BöhmBadri N. DubeyJutta NesperTilman SchirmerSebastian HillerUrs JenalNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020) |
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Science Q Andreas Kaczmarczyk Antje M. Hempel Christoph von Arx Raphael Böhm Badri N. Dubey Jutta Nesper Tilman Schirmer Sebastian Hiller Urs Jenal Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter |
description |
Bacteria adapt their growth rate to their metabolic status and environmental conditions by modulating the length of their G1 period. Here the authors show that an increase in c-di-GMP concentration modulates the activity of kinase ShkA and transcription factor TacA, thus enabling G1/S transition in Caulobacter. |
format |
article |
author |
Andreas Kaczmarczyk Antje M. Hempel Christoph von Arx Raphael Böhm Badri N. Dubey Jutta Nesper Tilman Schirmer Sebastian Hiller Urs Jenal |
author_facet |
Andreas Kaczmarczyk Antje M. Hempel Christoph von Arx Raphael Böhm Badri N. Dubey Jutta Nesper Tilman Schirmer Sebastian Hiller Urs Jenal |
author_sort |
Andreas Kaczmarczyk |
title |
Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter |
title_short |
Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter |
title_full |
Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter |
title_fullStr |
Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter |
title_full_unstemmed |
Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter |
title_sort |
precise timing of transcription by c-di-gmp coordinates cell cycle and morphogenesis in caulobacter |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/a8b0383615d04194986ba09c5f07fc8e |
work_keys_str_mv |
AT andreaskaczmarczyk precisetimingoftranscriptionbycdigmpcoordinatescellcycleandmorphogenesisincaulobacter AT antjemhempel precisetimingoftranscriptionbycdigmpcoordinatescellcycleandmorphogenesisincaulobacter AT christophvonarx precisetimingoftranscriptionbycdigmpcoordinatescellcycleandmorphogenesisincaulobacter AT raphaelbohm precisetimingoftranscriptionbycdigmpcoordinatescellcycleandmorphogenesisincaulobacter AT badrindubey precisetimingoftranscriptionbycdigmpcoordinatescellcycleandmorphogenesisincaulobacter AT juttanesper precisetimingoftranscriptionbycdigmpcoordinatescellcycleandmorphogenesisincaulobacter AT tilmanschirmer precisetimingoftranscriptionbycdigmpcoordinatescellcycleandmorphogenesisincaulobacter AT sebastianhiller precisetimingoftranscriptionbycdigmpcoordinatescellcycleandmorphogenesisincaulobacter AT ursjenal precisetimingoftranscriptionbycdigmpcoordinatescellcycleandmorphogenesisincaulobacter |
_version_ |
1718389888831717376 |