Immunology of biodegradable nanoparticles: a brief overview on a wide growing field

Immunity is continuously evolving by evolutionary mechanisms shaped by pathogenic stimuli of different kinds. Man-made nanomaterials (NMs) have been developed in the last decades and represent a novel challenge for our immune system, especially when applied to medical science. Toxicological studies...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Anissa Pisani, Giuseppe Bardi
Formato:	article
Lenguaje:	EN
Publicado:	Open Exploration Publishing Inc. 2021
Materias:	immune system nanoparticles inflammation cytokines protein corona Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/a8b2e748d52e4b5c997e4b46410fb69c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a8b2e748d52e4b5c997e4b46410fb69c
record_format	dspace
spelling	oai:doaj.org-article:a8b2e748d52e4b5c997e4b46410fb69c2021-11-24T01:45:17ZImmunology of biodegradable nanoparticles: a brief overview on a wide growing field10.37349/ei.2021.000062768-6655https://doaj.org/article/a8b2e748d52e4b5c997e4b46410fb69c2021-04-01T00:00:00Zhttps://www.explorationpub.com/Journals/ei/Article/10036https://doaj.org/toc/2768-6655Immunity is continuously evolving by evolutionary mechanisms shaped by pathogenic stimuli of different kinds. Man-made nanomaterials (NMs) have been developed in the last decades and represent a novel challenge for our immune system, especially when applied to medical science. Toxicological studies of such nanoparticles (NPs) revealed that size, shape, and surface chemistry are key parameters to understand their noxious effects on cellular mechanisms. Less is known on the immune reactions to NMs since prolonged exposure data are not so detailed as the results for acute administration. The importance of immunity to biocompatible NPs is underlined by their increasing use as drug or gene delivery carriers in common pharmaceutical preparations and vaccines. In the latter case, the immunomodulatory properties of NMs allow their use also as efficient adjuvants to enhance the innate immune response. In the current manuscript, the authors discuss the main concepts in this fast-growing field by restricting our view to NMs with consolidated application in biomedicine.Anissa PisaniGiuseppe BardiOpen Exploration Publishing Inc.articleimmune systemnanoparticlesinflammationcytokinesprotein coronaImmunologic diseases. AllergyRC581-607ENExploration of Immunology, Vol 1, Iss 1, Pp 48-60 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	immune system nanoparticles inflammation cytokines protein corona Immunologic diseases. Allergy RC581-607
spellingShingle	immune system nanoparticles inflammation cytokines protein corona Immunologic diseases. Allergy RC581-607 Anissa Pisani Giuseppe Bardi Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
description	Immunity is continuously evolving by evolutionary mechanisms shaped by pathogenic stimuli of different kinds. Man-made nanomaterials (NMs) have been developed in the last decades and represent a novel challenge for our immune system, especially when applied to medical science. Toxicological studies of such nanoparticles (NPs) revealed that size, shape, and surface chemistry are key parameters to understand their noxious effects on cellular mechanisms. Less is known on the immune reactions to NMs since prolonged exposure data are not so detailed as the results for acute administration. The importance of immunity to biocompatible NPs is underlined by their increasing use as drug or gene delivery carriers in common pharmaceutical preparations and vaccines. In the latter case, the immunomodulatory properties of NMs allow their use also as efficient adjuvants to enhance the innate immune response. In the current manuscript, the authors discuss the main concepts in this fast-growing field by restricting our view to NMs with consolidated application in biomedicine.
format	article
author	Anissa Pisani Giuseppe Bardi
author_facet	Anissa Pisani Giuseppe Bardi
author_sort	Anissa Pisani
title	Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
title_short	Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
title_full	Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
title_fullStr	Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
title_full_unstemmed	Immunology of biodegradable nanoparticles: a brief overview on a wide growing field
title_sort	immunology of biodegradable nanoparticles: a brief overview on a wide growing field
publisher	Open Exploration Publishing Inc.
publishDate	2021
url	https://doaj.org/article/a8b2e748d52e4b5c997e4b46410fb69c
work_keys_str_mv	AT anissapisani immunologyofbiodegradablenanoparticlesabriefoverviewonawidegrowingfield AT giuseppebardi immunologyofbiodegradablenanoparticlesabriefoverviewonawidegrowingfield
_version_	1718416053595275264

Immunology of biodegradable nanoparticles: a brief overview on a wide growing field

Ejemplares similares