Long-Term Evolution of <named-content content-type="genus-species">Burkholderia multivorans</named-content> during a Chronic Cystic Fibrosis Infection Reveals Shifting Forces of Selection

Long-Term Evolution of <named-content content-type="genus-species">Burkholderia multivorans</named-content> during a Chronic Cystic Fibrosis Infection Reveals Shifting Forces of Selection

ABSTRACT Burkholderia multivorans is an opportunistic pathogen capable of causing severe disease in patients with cystic fibrosis (CF). Patients may be chronically infected for years, during which the bacterial population evolves in response to unknown forces. Here we analyze the genomic and functio...

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Bibliographic Details
Main Authors: Inês N. Silva, Pedro M. Santos, Mário R. Santos, James E. A. Zlosnik, David P. Speert, Sean W. Buskirk, Eric L. Bruger, Christopher M. Waters, Vaughn S. Cooper, Leonilde M. Moreira
Format: article
Language:EN
Published: American Society for Microbiology 2016
Subjects:
Burkholderia multivorans
biofilm
c-di-GMP signaling
chronic infection
cystic fibrosis
evolution
Microbiology
QR1-502
Online Access:https://doaj.org/article/a8b33f07da31459b839fd83a285e7e3b
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