Role of steroids in critically-ill sepsis patients: a review article and literature to review

Sepsis, a life-threatening condition, commonly affecting critically ill patients, is a major cause of death worldwide. It is thus of great importance to determine the optimum management to cure this condition. This review article summarizes the role and effects of corticosteroids in the treatment of...

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Autores principales: Mohsin Mirza, Maryam Zafar, Mariam Siddiqui, Anum Abbas, Joseph Nahas, Muazzam Mirza, Abubakar Tauseef
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Lenguaje:EN
Publicado: Taylor & Francis Group 2021
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Acceso en línea:https://doaj.org/article/a8b3ec3e0eb84d48a4acf294d6e93c45
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spelling oai:doaj.org-article:a8b3ec3e0eb84d48a4acf294d6e93c452021-11-17T14:21:57ZRole of steroids in critically-ill sepsis patients: a review article and literature to review2000-966610.1080/20009666.2021.1964164https://doaj.org/article/a8b3ec3e0eb84d48a4acf294d6e93c452021-11-01T00:00:00Zhttp://dx.doi.org/10.1080/20009666.2021.1964164https://doaj.org/toc/2000-9666Sepsis, a life-threatening condition, commonly affecting critically ill patients, is a major cause of death worldwide. It is thus of great importance to determine the optimum management to cure this condition. This review article summarizes the role and effects of corticosteroids in the treatment of sepsis and septic shock, and to determine its mortality benefits. We used PubMed, Google scholar, Scopus, and Embase databases for literature review, and terminologies commonly searched were ‘sepsis’, ‘septic shock’, ‘therapeutic use’ and ‘corticosteroids’. In this review article, we reviewed a total of eight different articles being done in last 10 years, relevant to the clinical outcome and effects of corticosteroids. Among those, two demonstrated improved clinical outcomes, two showed both improved clinical outcomes and decreased mortality, three showed increased adverse effects, and the remaining one showed unequivocal results.Mohsin MirzaMaryam ZafarMariam SiddiquiAnum AbbasJoseph NahasMuazzam MirzaAbubakar TauseefTaylor & Francis Grouparticlerolesteroidsepsisreviewliteraurecritically illInternal medicineRC31-1245ENJournal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 6, Pp 825-829 (2021)
institution DOAJ
collection DOAJ
language EN
topic role
steroid
sepsis
review
literaure
critically ill
Internal medicine
RC31-1245
spellingShingle role
steroid
sepsis
review
literaure
critically ill
Internal medicine
RC31-1245
Mohsin Mirza
Maryam Zafar
Mariam Siddiqui
Anum Abbas
Joseph Nahas
Muazzam Mirza
Abubakar Tauseef
Role of steroids in critically-ill sepsis patients: a review article and literature to review
description Sepsis, a life-threatening condition, commonly affecting critically ill patients, is a major cause of death worldwide. It is thus of great importance to determine the optimum management to cure this condition. This review article summarizes the role and effects of corticosteroids in the treatment of sepsis and septic shock, and to determine its mortality benefits. We used PubMed, Google scholar, Scopus, and Embase databases for literature review, and terminologies commonly searched were ‘sepsis’, ‘septic shock’, ‘therapeutic use’ and ‘corticosteroids’. In this review article, we reviewed a total of eight different articles being done in last 10 years, relevant to the clinical outcome and effects of corticosteroids. Among those, two demonstrated improved clinical outcomes, two showed both improved clinical outcomes and decreased mortality, three showed increased adverse effects, and the remaining one showed unequivocal results.
format article
author Mohsin Mirza
Maryam Zafar
Mariam Siddiqui
Anum Abbas
Joseph Nahas
Muazzam Mirza
Abubakar Tauseef
author_facet Mohsin Mirza
Maryam Zafar
Mariam Siddiqui
Anum Abbas
Joseph Nahas
Muazzam Mirza
Abubakar Tauseef
author_sort Mohsin Mirza
title Role of steroids in critically-ill sepsis patients: a review article and literature to review
title_short Role of steroids in critically-ill sepsis patients: a review article and literature to review
title_full Role of steroids in critically-ill sepsis patients: a review article and literature to review
title_fullStr Role of steroids in critically-ill sepsis patients: a review article and literature to review
title_full_unstemmed Role of steroids in critically-ill sepsis patients: a review article and literature to review
title_sort role of steroids in critically-ill sepsis patients: a review article and literature to review
publisher Taylor & Francis Group
publishDate 2021
url https://doaj.org/article/a8b3ec3e0eb84d48a4acf294d6e93c45
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