Vaccination with Plasmodium knowlesi AMA1 formulated in the novel adjuvant co-vaccine HT™ protects against blood-stage challenge in rhesus macaques.
Plasmodium falciparum apical membrane antigen 1 (PfAMA1) is a leading blood stage vaccine candidate. Plasmodium knowlesi AMA1 (PkAMA1) was produced and purified using similar methodology as for clinical grade PfAMA1 yielding a pure, conformational intact protein. Combined with the adjuvant CoVaccine...
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Autores principales: | Muzamil Mahdi Abdel Hamid, Edmond J Remarque, Leonie M van Duivenvoorde, Nicole van der Werff, Vanessa Walraven, Bart W Faber, Clemens H M Kocken, Alan W Thomas |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/a8c56c55916947b0916bc7aab680d96b |
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