$Value of markers of bone tissue resorption in the prognosis of development of slow consolidation of fractures of long bones of extremities$
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Value of markers of bone tissue resorption in the prognosis of development of slow consolidation of fractures of long bones of extremities

The objective of the work was to study value of indicators of pyridinoline and dezoksipyridinoline in the prognosis of development of slow consolidation of fractures of long bones of extremities. We carried out the research of markers of resorption of bone tissue in 75 patients of 16-55 years with f...

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Autores principales:	A. M. Miromanov, K. A. Gusev, S. A. Uskov
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2013
Materias:	fractures of long bones of extremities consolidation disorder prognosis Science Q
Acceso en línea:	https://doaj.org/article/a8c936d8b96244a197a0903d2781c6af
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spelling	oai:doaj.org-article:a8c936d8b96244a197a0903d2781c6af2021-11-23T06:14:27ZValue of markers of bone tissue resorption in the prognosis of development of slow consolidation of fractures of long bones of extremities2541-94202587-9596https://doaj.org/article/a8c936d8b96244a197a0903d2781c6af2013-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1526https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The objective of the work was to study value of indicators of pyridinoline and dezoksipyridinoline in the prognosis of development of slow consolidation of fractures of long bones of extremities. We carried out the research of markers of resorption of bone tissue in 75 patients of 16-55 years with fractures of long bones of extremities in postoperative period. The first group included. 44 patients with non-complicated course of posttraumatic period. The second group (n = 31) included patients with disorder of consolidation of fractures in late posttraumatic period (slow consolidation). Control group included. 30 nearly healthy people of 18-35 years. Groups of patients were compared by sex, age, time of getting the injury, character of fractures and. the treatment they got. The criteria of excluding out of the research were patients with any concomitant pathology and. also women in menopause. The researches were realized on the 2nd and. the 10th day of posttraumatic period. Statistical processing of the data was realized with help of «BIOSTAT». The analysis of data between the groups of patients in different terms of posttraumatic period was carried out with, help of Newman - Keuls criteria. To compare indices of patients with, complicated and. non-complicated. course of fractures of long bones of extremities we used Mann - Whitney criteria. The differences were considered statistically sigificans at p < 0,05. It was determined that at the level of pyridinoline in blood serum more than 15 % and of deoxypyridinoline in urine more than 35 % of control values on the 10th day after trauma the disorder of consolidation of fractures in late postoperative period is prognosed. Determination of indices of pyridinoline and. deoxypyridinoline patients with fractures of long bones of extremities on the 10th day of posttraumatic period allows to prognose development of slow consolidation of fractures that can allow to realize preventive prophylactic and. treatment measures aimed at precaution of development of disorders of consolidation.A. M. MiromanovK. A. GusevS. A. UskovScientific Сentre for Family Health and Human Reproduction Problemsarticlefractures of long bones of extremitiesconsolidation disorderprognosisScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2(1), Pp 53-56 (2013)
institution	DOAJ
collection	DOAJ
language	RU
topic	fractures of long bones of extremities consolidation disorder prognosis Science Q
spellingShingle	fractures of long bones of extremities consolidation disorder prognosis Science Q A. M. Miromanov K. A. Gusev S. A. Uskov Value of markers of bone tissue resorption in the prognosis of development of slow consolidation of fractures of long bones of extremities
description	The objective of the work was to study value of indicators of pyridinoline and dezoksipyridinoline in the prognosis of development of slow consolidation of fractures of long bones of extremities. We carried out the research of markers of resorption of bone tissue in 75 patients of 16-55 years with fractures of long bones of extremities in postoperative period. The first group included. 44 patients with non-complicated course of posttraumatic period. The second group (n = 31) included patients with disorder of consolidation of fractures in late posttraumatic period (slow consolidation). Control group included. 30 nearly healthy people of 18-35 years. Groups of patients were compared by sex, age, time of getting the injury, character of fractures and. the treatment they got. The criteria of excluding out of the research were patients with any concomitant pathology and. also women in menopause. The researches were realized on the 2nd and. the 10th day of posttraumatic period. Statistical processing of the data was realized with help of «BIOSTAT». The analysis of data between the groups of patients in different terms of posttraumatic period was carried out with, help of Newman - Keuls criteria. To compare indices of patients with, complicated and. non-complicated. course of fractures of long bones of extremities we used Mann - Whitney criteria. The differences were considered statistically sigificans at p < 0,05. It was determined that at the level of pyridinoline in blood serum more than 15 % and of deoxypyridinoline in urine more than 35 % of control values on the 10th day after trauma the disorder of consolidation of fractures in late postoperative period is prognosed. Determination of indices of pyridinoline and. deoxypyridinoline patients with fractures of long bones of extremities on the 10th day of posttraumatic period allows to prognose development of slow consolidation of fractures that can allow to realize preventive prophylactic and. treatment measures aimed at precaution of development of disorders of consolidation.
format	article
author	A. M. Miromanov K. A. Gusev S. A. Uskov
author_facet	A. M. Miromanov K. A. Gusev S. A. Uskov
author_sort	A. M. Miromanov
title	Value of markers of bone tissue resorption in the prognosis of development of slow consolidation of fractures of long bones of extremities
title_short	Value of markers of bone tissue resorption in the prognosis of development of slow consolidation of fractures of long bones of extremities
title_full	Value of markers of bone tissue resorption in the prognosis of development of slow consolidation of fractures of long bones of extremities
title_fullStr	Value of markers of bone tissue resorption in the prognosis of development of slow consolidation of fractures of long bones of extremities
title_full_unstemmed	Value of markers of bone tissue resorption in the prognosis of development of slow consolidation of fractures of long bones of extremities
title_sort	value of markers of bone tissue resorption in the prognosis of development of slow consolidation of fractures of long bones of extremities
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2013
url	https://doaj.org/article/a8c936d8b96244a197a0903d2781c6af
work_keys_str_mv	AT ammiromanov valueofmarkersofbonetissueresorptionintheprognosisofdevelopmentofslowconsolidationoffracturesoflongbonesofextremities AT kagusev valueofmarkersofbonetissueresorptionintheprognosisofdevelopmentofslowconsolidationoffracturesoflongbonesofextremities AT sauskov valueofmarkersofbonetissueresorptionintheprognosisofdevelopmentofslowconsolidationoffracturesoflongbonesofextremities
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Value of markers of bone tissue resorption in the prognosis of development of slow consolidation of fractures of long bones of extremities

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