High proliferation and delamination during skin epidermal stratification

How the developing skin epidermis is transformed from a simple single-layered epithelium to a complex and stratified barrier is still an open question. Here, the authors provide a model based on high proliferation and delamination of the keratinocyte progenitors that support the stratification proce...

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Autores principales: Mareike Damen, Lisa Wirtz, Ekaterina Soroka, Houda Khatif, Christian Kukat, Benjamin D. Simons, Hisham Bazzi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a8d8b4dfc80449d585d4094cbc088097
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spelling oai:doaj.org-article:a8d8b4dfc80449d585d4094cbc0880972021-12-02T15:00:50ZHigh proliferation and delamination during skin epidermal stratification10.1038/s41467-021-23386-42041-1723https://doaj.org/article/a8d8b4dfc80449d585d4094cbc0880972021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23386-4https://doaj.org/toc/2041-1723How the developing skin epidermis is transformed from a simple single-layered epithelium to a complex and stratified barrier is still an open question. Here, the authors provide a model based on high proliferation and delamination of the keratinocyte progenitors that support the stratification process.Mareike DamenLisa WirtzEkaterina SorokaHouda KhatifChristian KukatBenjamin D. SimonsHisham BazziNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mareike Damen
Lisa Wirtz
Ekaterina Soroka
Houda Khatif
Christian Kukat
Benjamin D. Simons
Hisham Bazzi
High proliferation and delamination during skin epidermal stratification
description How the developing skin epidermis is transformed from a simple single-layered epithelium to a complex and stratified barrier is still an open question. Here, the authors provide a model based on high proliferation and delamination of the keratinocyte progenitors that support the stratification process.
format article
author Mareike Damen
Lisa Wirtz
Ekaterina Soroka
Houda Khatif
Christian Kukat
Benjamin D. Simons
Hisham Bazzi
author_facet Mareike Damen
Lisa Wirtz
Ekaterina Soroka
Houda Khatif
Christian Kukat
Benjamin D. Simons
Hisham Bazzi
author_sort Mareike Damen
title High proliferation and delamination during skin epidermal stratification
title_short High proliferation and delamination during skin epidermal stratification
title_full High proliferation and delamination during skin epidermal stratification
title_fullStr High proliferation and delamination during skin epidermal stratification
title_full_unstemmed High proliferation and delamination during skin epidermal stratification
title_sort high proliferation and delamination during skin epidermal stratification
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a8d8b4dfc80449d585d4094cbc088097
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AT lisawirtz highproliferationanddelaminationduringskinepidermalstratification
AT ekaterinasoroka highproliferationanddelaminationduringskinepidermalstratification
AT houdakhatif highproliferationanddelaminationduringskinepidermalstratification
AT christiankukat highproliferationanddelaminationduringskinepidermalstratification
AT benjamindsimons highproliferationanddelaminationduringskinepidermalstratification
AT hishambazzi highproliferationanddelaminationduringskinepidermalstratification
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