Molecular programs of fibrotic change in aging human lung
Age is associated with increasing vulnerability to both acute and chronic lung diseases. Employing genomic analysis and live lung imaging, this study reveals a profile of increased cellular senescence, telomere shortening, and fibrosis-induced impaired alveolar function in the natural history of hum...
Guardado en:
Autores principales: | Seoyeon Lee, Mohammad Naimul Islam, Kaveh Boostanpour, Dvir Aran, Guangchun Jin, Stephanie Christenson, Michael A. Matthay, Walter L. Eckalbar, Daryle J. DePianto, Joseph R. Arron, Liam Magee, Sunita Bhattacharya, Rei Matsumoto, Masaru Kubota, Donna L. Farber, Jahar Bhattacharya, Paul J. Wolters, Mallar Bhattacharya |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/a8e19683da4c4b2a8b772edf8db594e5 |
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