Identification of Extracellular DNA-Binding Proteins in the Biofilm Matrix
ABSTRACT We developed a new approach that couples Southwestern blotting and mass spectrometry to discover proteins that bind extracellular DNA (eDNA) in bacterial biofilms. Using Staphylococcus aureus as a model pathogen, we identified proteins with known DNA-binding activity and uncovered a series...
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Main Authors: | , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2019
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Subjects: | |
Online Access: | https://doaj.org/article/a8e208da8e384b019ca1c75e6293f2c3 |
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