Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences

The unique biophysical properties of human cortical neurons that may underlie interlaminar communication are explored. With a focus on I h and layers 2&3, 3c, and 5, the authors show that L5 pyramidal neurons are better adapted than their superficial layer counterparts to track delta and theta f...

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Autores principales:	Homeira Moradi Chameh, Scott Rich, Lihua Wang, Fu-Der Chen, Liang Zhang, Peter L. Carlen, Shreejoy J. Tripathy, Taufik A. Valiante
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a8e5c0faab2d41e0b4f16f4ab7318934
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spelling	oai:doaj.org-article:a8e5c0faab2d41e0b4f16f4ab73189342021-12-02T16:51:30ZDiversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences10.1038/s41467-021-22741-92041-1723https://doaj.org/article/a8e5c0faab2d41e0b4f16f4ab73189342021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22741-9https://doaj.org/toc/2041-1723The unique biophysical properties of human cortical neurons that may underlie interlaminar communication are explored. With a focus on I h and layers 2&3, 3c, and 5, the authors show that L5 pyramidal neurons are better adapted than their superficial layer counterparts to track delta and theta frequency inputs.Homeira Moradi ChamehScott RichLihua WangFu-Der ChenLiang ZhangPeter L. CarlenShreejoy J. TripathyTaufik A. ValianteNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Homeira Moradi Chameh Scott Rich Lihua Wang Fu-Der Chen Liang Zhang Peter L. Carlen Shreejoy J. Tripathy Taufik A. Valiante Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences
description	The unique biophysical properties of human cortical neurons that may underlie interlaminar communication are explored. With a focus on I h and layers 2&3, 3c, and 5, the authors show that L5 pyramidal neurons are better adapted than their superficial layer counterparts to track delta and theta frequency inputs.
format	article
author	Homeira Moradi Chameh Scott Rich Lihua Wang Fu-Der Chen Liang Zhang Peter L. Carlen Shreejoy J. Tripathy Taufik A. Valiante
author_facet	Homeira Moradi Chameh Scott Rich Lihua Wang Fu-Der Chen Liang Zhang Peter L. Carlen Shreejoy J. Tripathy Taufik A. Valiante
author_sort	Homeira Moradi Chameh
title	Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences
title_short	Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences
title_full	Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences
title_fullStr	Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences
title_full_unstemmed	Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences
title_sort	diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a8e5c0faab2d41e0b4f16f4ab7318934
work_keys_str_mv	AT homeiramoradichameh diversityamongsthumancorticalpyramidalneuronsrevealedviatheirsagcurrentsandfrequencypreferences AT scottrich diversityamongsthumancorticalpyramidalneuronsrevealedviatheirsagcurrentsandfrequencypreferences AT lihuawang diversityamongsthumancorticalpyramidalneuronsrevealedviatheirsagcurrentsandfrequencypreferences AT fuderchen diversityamongsthumancorticalpyramidalneuronsrevealedviatheirsagcurrentsandfrequencypreferences AT liangzhang diversityamongsthumancorticalpyramidalneuronsrevealedviatheirsagcurrentsandfrequencypreferences AT peterlcarlen diversityamongsthumancorticalpyramidalneuronsrevealedviatheirsagcurrentsandfrequencypreferences AT shreejoyjtripathy diversityamongsthumancorticalpyramidalneuronsrevealedviatheirsagcurrentsandfrequencypreferences AT taufikavaliante diversityamongsthumancorticalpyramidalneuronsrevealedviatheirsagcurrentsandfrequencypreferences
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Diversity amongst human cortical pyramidal neurons revealed via their sag currents and frequency preferences

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