DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer
Shen and Korm et al. investigate the role of dihydrolipoamide S-succinyltransferase (DLST), a tricarboxylic acid (TCA) cycle enzyme, in the metabolic heterogeneity of triple negative breast cancer (TNBC) cell lines. They show that either depletion or inhibition of DLST in the dependent cells leads t...
Enregistré dans:
Auteurs principaux: | Ning Shen, Sovannarith Korm, Theodoros Karantanos, Dun Li, Xiaoyu Zhang, Eleni Ritou, Hanfei Xu, Andrew Lam, Justin English, Wei-Xing Zong, Ching-Ti Liu, Orian Shirihai, Hui Feng |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/a8e5c3aaebb34b0ca493310c2fcbbf13 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Mitochondrial TCA cycle metabolites control physiology and disease
par: Inmaculada Martínez-Reyes, et autres
Publié: (2020) -
FCPA and TCA: Introducing the Presumptions of Final Judgment and Joint Investigation
par: JAVIER CORONADO DÍAZ
Publié: (2019) -
TCA cycle remodeling drives proinflammatory signaling in humans with pulmonary tuberculosis.
par: Jeffrey M Collins, et autres
Publié: (2021) -
The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry
par: Xujun Liu, et autres
Publié: (2021) -
Gregg dictation
par: Leslie, Louis