Impact of the Extent of Surgical Resection on Patients With Intradural Extramedullary Bronchogenic Cysts: A Retrospective Institutional Experience and Review of the Literature

Intradural extramedullary bronchogenic cysts (IEBC) are rare congenital cystic lesions. The clinical manifestations, radiological characteristics, especially the optimal treatment regimen are not well-understood. We retrospectively analyzed a series of patients with confirmed IEBC in Tangdu hospital...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jinghui Liu, Yuan Wang, Chen Li, Peigang Ji, Shaochun Guo, Yulong Zhai, Na Wang, Miao Lou, Meng Xu, Min Chao, Fuqiang Feng, Ming Yan, Liang Wang
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	bronchogenic cyst intradural extramedullary intraspinal cyst endodermal cyst surgery Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/a8e923587614449498783fef54bf6fc8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a8e923587614449498783fef54bf6fc8
record_format	dspace
spelling	oai:doaj.org-article:a8e923587614449498783fef54bf6fc82021-12-02T06:41:53ZImpact of the Extent of Surgical Resection on Patients With Intradural Extramedullary Bronchogenic Cysts: A Retrospective Institutional Experience and Review of the Literature1664-229510.3389/fneur.2021.706742https://doaj.org/article/a8e923587614449498783fef54bf6fc82021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fneur.2021.706742/fullhttps://doaj.org/toc/1664-2295Intradural extramedullary bronchogenic cysts (IEBC) are rare congenital cystic lesions. The clinical manifestations, radiological characteristics, especially the optimal treatment regimen are not well-understood. We retrospectively analyzed a series of patients with confirmed IEBC in Tangdu hospital and reviewed the published works to gain a comprehensive understanding of IEBC. In our institution, nine consecutive patients had pathologically confirmed IEBC between 2005 and 2018. We also identified 27 patients from previous studies. The most common presentations on magnetic resonance imaging (MRI) were hypointensity on T1-weighted images (T1WI), hyperintensity on T2-weighted images(T2WI), and no improvement on T1WI contrast-enhanced with gadolinium (94.4%). All patients in our center and the patients we reviewed received surgical resection; gross total resection (GTR) and partial resection (PR) were achieved in 20 (55.6%) and 16 (44.4%) patients, respectively. The symptom remission rate of patients who underwent GTR was 100%, which was similar to those who underwent PR (93.8%) (P = 0.457). The recurrence rate was 12.5% in the group who underwent PR and nil after GTR (P = 0.202). According to our current investigation, the surgical resection degree is irrelevant to the symptom remission rate. Therefore, we suggest that total resection should not be recommended for cases with tight adhesion. For patients with PR, longer follow-up will be necessary to determine the long-term outcome.Jinghui LiuYuan WangChen LiPeigang JiShaochun GuoYulong ZhaiNa WangMiao LouMeng XuMin ChaoFuqiang FengMing YanLiang WangFrontiers Media S.A.articlebronchogenic cystintradural extramedullaryintraspinal cystendodermal cystsurgeryNeurology. Diseases of the nervous systemRC346-429ENFrontiers in Neurology, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	bronchogenic cyst intradural extramedullary intraspinal cyst endodermal cyst surgery Neurology. Diseases of the nervous system RC346-429
spellingShingle	bronchogenic cyst intradural extramedullary intraspinal cyst endodermal cyst surgery Neurology. Diseases of the nervous system RC346-429 Jinghui Liu Yuan Wang Chen Li Peigang Ji Shaochun Guo Yulong Zhai Na Wang Miao Lou Meng Xu Min Chao Fuqiang Feng Ming Yan Liang Wang Impact of the Extent of Surgical Resection on Patients With Intradural Extramedullary Bronchogenic Cysts: A Retrospective Institutional Experience and Review of the Literature
description	Intradural extramedullary bronchogenic cysts (IEBC) are rare congenital cystic lesions. The clinical manifestations, radiological characteristics, especially the optimal treatment regimen are not well-understood. We retrospectively analyzed a series of patients with confirmed IEBC in Tangdu hospital and reviewed the published works to gain a comprehensive understanding of IEBC. In our institution, nine consecutive patients had pathologically confirmed IEBC between 2005 and 2018. We also identified 27 patients from previous studies. The most common presentations on magnetic resonance imaging (MRI) were hypointensity on T1-weighted images (T1WI), hyperintensity on T2-weighted images(T2WI), and no improvement on T1WI contrast-enhanced with gadolinium (94.4%). All patients in our center and the patients we reviewed received surgical resection; gross total resection (GTR) and partial resection (PR) were achieved in 20 (55.6%) and 16 (44.4%) patients, respectively. The symptom remission rate of patients who underwent GTR was 100%, which was similar to those who underwent PR (93.8%) (P = 0.457). The recurrence rate was 12.5% in the group who underwent PR and nil after GTR (P = 0.202). According to our current investigation, the surgical resection degree is irrelevant to the symptom remission rate. Therefore, we suggest that total resection should not be recommended for cases with tight adhesion. For patients with PR, longer follow-up will be necessary to determine the long-term outcome.
format	article
author	Jinghui Liu Yuan Wang Chen Li Peigang Ji Shaochun Guo Yulong Zhai Na Wang Miao Lou Meng Xu Min Chao Fuqiang Feng Ming Yan Liang Wang
author_facet	Jinghui Liu Yuan Wang Chen Li Peigang Ji Shaochun Guo Yulong Zhai Na Wang Miao Lou Meng Xu Min Chao Fuqiang Feng Ming Yan Liang Wang
author_sort	Jinghui Liu
title	Impact of the Extent of Surgical Resection on Patients With Intradural Extramedullary Bronchogenic Cysts: A Retrospective Institutional Experience and Review of the Literature
title_short	Impact of the Extent of Surgical Resection on Patients With Intradural Extramedullary Bronchogenic Cysts: A Retrospective Institutional Experience and Review of the Literature
title_full	Impact of the Extent of Surgical Resection on Patients With Intradural Extramedullary Bronchogenic Cysts: A Retrospective Institutional Experience and Review of the Literature
title_fullStr	Impact of the Extent of Surgical Resection on Patients With Intradural Extramedullary Bronchogenic Cysts: A Retrospective Institutional Experience and Review of the Literature
title_full_unstemmed	Impact of the Extent of Surgical Resection on Patients With Intradural Extramedullary Bronchogenic Cysts: A Retrospective Institutional Experience and Review of the Literature
title_sort	impact of the extent of surgical resection on patients with intradural extramedullary bronchogenic cysts: a retrospective institutional experience and review of the literature
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/a8e923587614449498783fef54bf6fc8
work_keys_str_mv	AT jinghuiliu impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature AT yuanwang impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature AT chenli impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature AT peigangji impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature AT shaochunguo impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature AT yulongzhai impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature AT nawang impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature AT miaolou impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature AT mengxu impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature AT minchao impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature AT fuqiangfeng impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature AT mingyan impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature AT liangwang impactoftheextentofsurgicalresectiononpatientswithintraduralextramedullarybronchogeniccystsaretrospectiveinstitutionalexperienceandreviewoftheliterature
_version_	1718399770899251200

Impact of the Extent of Surgical Resection on Patients With Intradural Extramedullary Bronchogenic Cysts: A Retrospective Institutional Experience and Review of the Literature

Ejemplares similares