Predicting distant metastasis and chemotherapy benefit in locally advanced rectal cancer

Distant metastasis (DM) is the main cause of treatment failure in locally advanced rectal cancer. Here, the authors developed and validated a radiomic signature (RS) for prediction of DM within a multicenter dataset, and suggest that it may help with stratification of patients who might benefit from...

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Autores principales: Zhenyu Liu, Xiaochun Meng, Hongmei Zhang, Zhenhui Li, Jiangang Liu, Kai Sun, Yankai Meng, Weixing Dai, Peiyi Xie, Yingying Ding, Meiyun Wang, Guoxiang Cai, Jie Tian
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a8eb14a840194d488c3ebf44a273a6e3
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Sumario:Distant metastasis (DM) is the main cause of treatment failure in locally advanced rectal cancer. Here, the authors developed and validated a radiomic signature (RS) for prediction of DM within a multicenter dataset, and suggest that it may help with stratification of patients who might benefit from adjuvant chemotherapy for DM.