Deimmunization of flagellin for repeated administration as a vaccine adjuvant
Abstract Flagellin, a protein-based Toll-like receptor agonist, is a versatile adjuvant applicable to wide spectrum of vaccines and immunotherapies. Given reiterated treatments of immunogenic biopharmaceuticals should lead to antibody responses precluding repeated administration, the development of...
Guardado en:
Autores principales: | Koemchhoy Khim, Yong Jun Bang, Sao Puth, Yoonjoo Choi, Youn Suhk Lee, Kwangjoon Jeong, Shee Eun Lee, Joon Haeng Rhee |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/a8f24b6ddcc2499695bfd6ace50b7b97 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
A deimmunized and pharmacologically optimized Toll-like receptor 5 agonist for therapeutic applications
por: Vadim Mett, et al.
Publicado: (2021) -
FliS/flagellin/FliW heterotrimer couples type III secretion and flagellin homeostasis
por: Florian Altegoer, et al.
Publicado: (2018) -
Role of DegQ in differential stability of flagellin subunits in Vibrio vulnificus
por: You-Chul Jung, et al.
Publicado: (2021) -
Dual-linker gold nanoparticles as adjuvanting carriers for multivalent display of recombinant influenza hemagglutinin trimers and flagellin improve the immunological responses in vivo and in vitro
por: Wang C, et al.
Publicado: (2017) -
The Role of Flagellin B in Vibrio anguillarum-Induced Intestinal Immunity and Functional Domain Identification
por: Quanxin Gao, et al.
Publicado: (2021)