Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis

Gastroschisis is a congenital abdominal wall defect that presents an increasing occurrence at great cost for the health system. The aim of the study is to detect the main factors of an unfavorable evolution in the case of gastroschisis and to find the best predictors of death. Methods: we conducted...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Elena Ţarcă, Solange Tamara Roșu, Elena Cojocaru, Laura Trandafir, Alina Costina Luca, Valeriu Vasile Lupu, Ștefana Maria Moisă, Valentin Munteanu, Lăcrămioara Ionela Butnariu, Viorel Ţarcă
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	gastroschisis morbidity mortality outcome Medicine R
Acceso en línea:	https://doaj.org/article/a8f692cdd8eb48bcb36e0c8baa50e901
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a8f692cdd8eb48bcb36e0c8baa50e901
record_format	dspace
spelling	oai:doaj.org-article:a8f692cdd8eb48bcb36e0c8baa50e9012021-11-25T18:07:42ZStatistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis10.3390/jpm111111682075-4426https://doaj.org/article/a8f692cdd8eb48bcb36e0c8baa50e9012021-11-01T00:00:00Zhttps://www.mdpi.com/2075-4426/11/11/1168https://doaj.org/toc/2075-4426Gastroschisis is a congenital abdominal wall defect that presents an increasing occurrence at great cost for the health system. The aim of the study is to detect the main factors of an unfavorable evolution in the case of gastroschisis and to find the best predictors of death. Methods: we conducted a retrospective cohort study of neonates with gastroschisis treated in a tertiary pediatric center during the last 30 years; 159 patients were eligible for the study. Logistic regression was used to determine the risk of death, estimated based on independent variables previously validated by the chi-square test. Results: if the birth weight is below normal, then we find an increased risk (4.908 times) of evolution to death. Similarly, the risk of death is 7.782 times higher in the case of developing abdominal compartment syndrome, about 3 times in the case of sepsis and 7.883 times in the case of bronchopneumonia. All four independent variables contributed 47.6% to the risk of death. Conclusion: although in the past 30 years in our country we have seen transformational improvements in outcome of gastroschisis, survival rates increasing from 26% to 52%, some factors may still be ameliorated for a better outcome.Elena ŢarcăSolange Tamara RoșuElena CojocaruLaura TrandafirAlina Costina LucaValeriu Vasile LupuȘtefana Maria MoisăValentin MunteanuLăcrămioara Ionela ButnariuViorel ŢarcăMDPI AGarticlegastroschisismorbiditymortalityoutcomeMedicineRENJournal of Personalized Medicine, Vol 11, Iss 1168, p 1168 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	gastroschisis morbidity mortality outcome Medicine R
spellingShingle	gastroschisis morbidity mortality outcome Medicine R Elena Ţarcă Solange Tamara Roșu Elena Cojocaru Laura Trandafir Alina Costina Luca Valeriu Vasile Lupu Ștefana Maria Moisă Valentin Munteanu Lăcrămioara Ionela Butnariu Viorel Ţarcă Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis
description	Gastroschisis is a congenital abdominal wall defect that presents an increasing occurrence at great cost for the health system. The aim of the study is to detect the main factors of an unfavorable evolution in the case of gastroschisis and to find the best predictors of death. Methods: we conducted a retrospective cohort study of neonates with gastroschisis treated in a tertiary pediatric center during the last 30 years; 159 patients were eligible for the study. Logistic regression was used to determine the risk of death, estimated based on independent variables previously validated by the chi-square test. Results: if the birth weight is below normal, then we find an increased risk (4.908 times) of evolution to death. Similarly, the risk of death is 7.782 times higher in the case of developing abdominal compartment syndrome, about 3 times in the case of sepsis and 7.883 times in the case of bronchopneumonia. All four independent variables contributed 47.6% to the risk of death. Conclusion: although in the past 30 years in our country we have seen transformational improvements in outcome of gastroschisis, survival rates increasing from 26% to 52%, some factors may still be ameliorated for a better outcome.
format	article
author	Elena Ţarcă Solange Tamara Roșu Elena Cojocaru Laura Trandafir Alina Costina Luca Valeriu Vasile Lupu Ștefana Maria Moisă Valentin Munteanu Lăcrămioara Ionela Butnariu Viorel Ţarcă
author_facet	Elena Ţarcă Solange Tamara Roșu Elena Cojocaru Laura Trandafir Alina Costina Luca Valeriu Vasile Lupu Ștefana Maria Moisă Valentin Munteanu Lăcrămioara Ionela Butnariu Viorel Ţarcă
author_sort	Elena Ţarcă
title	Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis
title_short	Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis
title_full	Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis
title_fullStr	Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis
title_full_unstemmed	Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis
title_sort	statistical analysis of the main risk factors of an unfavorable evolution in gastroschisis
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/a8f692cdd8eb48bcb36e0c8baa50e901
work_keys_str_mv	AT elenatarca statisticalanalysisofthemainriskfactorsofanunfavorableevolutioningastroschisis AT solangetamararosu statisticalanalysisofthemainriskfactorsofanunfavorableevolutioningastroschisis AT elenacojocaru statisticalanalysisofthemainriskfactorsofanunfavorableevolutioningastroschisis AT lauratrandafir statisticalanalysisofthemainriskfactorsofanunfavorableevolutioningastroschisis AT alinacostinaluca statisticalanalysisofthemainriskfactorsofanunfavorableevolutioningastroschisis AT valeriuvasilelupu statisticalanalysisofthemainriskfactorsofanunfavorableevolutioningastroschisis AT stefanamariamoisa statisticalanalysisofthemainriskfactorsofanunfavorableevolutioningastroschisis AT valentinmunteanu statisticalanalysisofthemainriskfactorsofanunfavorableevolutioningastroschisis AT lacramioaraionelabutnariu statisticalanalysisofthemainriskfactorsofanunfavorableevolutioningastroschisis AT vioreltarca statisticalanalysisofthemainriskfactorsofanunfavorableevolutioningastroschisis
_version_	1718411634768084992

Statistical Analysis of the Main Risk Factors of an Unfavorable Evolution in Gastroschisis

Ejemplares similares