Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM

The increasing accessibility of single cell omics technologies beyond transcriptomics demands parallel advances in analysis. Here, the authors introduce STREAM, a pipeline for reconstruction and visualization of differentiation trajectories from both single-cell RNA-seq and ATAC-seq data.

Guardado en:
Detalles Bibliográficos
Autores principales: Huidong Chen, Luca Albergante, Jonathan Y. Hsu, Caleb A. Lareau, Giosuè Lo Bosco, Jihong Guan, Shuigeng Zhou, Alexander N. Gorban, Daniel E. Bauer, Martin J. Aryee, David M. Langenau, Andrei Zinovyev, Jason D. Buenrostro, Guo-Cheng Yuan, Luca Pinello
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/a8fc084be2f940a8842ac27783508d69
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:a8fc084be2f940a8842ac27783508d69
record_format dspace
spelling oai:doaj.org-article:a8fc084be2f940a8842ac27783508d692021-12-02T17:01:28ZSingle-cell trajectories reconstruction, exploration and mapping of omics data with STREAM10.1038/s41467-019-09670-42041-1723https://doaj.org/article/a8fc084be2f940a8842ac27783508d692019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09670-4https://doaj.org/toc/2041-1723The increasing accessibility of single cell omics technologies beyond transcriptomics demands parallel advances in analysis. Here, the authors introduce STREAM, a pipeline for reconstruction and visualization of differentiation trajectories from both single-cell RNA-seq and ATAC-seq data.Huidong ChenLuca AlberganteJonathan Y. HsuCaleb A. LareauGiosuè Lo BoscoJihong GuanShuigeng ZhouAlexander N. GorbanDaniel E. BauerMartin J. AryeeDavid M. LangenauAndrei ZinovyevJason D. BuenrostroGuo-Cheng YuanLuca PinelloNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Huidong Chen
Luca Albergante
Jonathan Y. Hsu
Caleb A. Lareau
Giosuè Lo Bosco
Jihong Guan
Shuigeng Zhou
Alexander N. Gorban
Daniel E. Bauer
Martin J. Aryee
David M. Langenau
Andrei Zinovyev
Jason D. Buenrostro
Guo-Cheng Yuan
Luca Pinello
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM
description The increasing accessibility of single cell omics technologies beyond transcriptomics demands parallel advances in analysis. Here, the authors introduce STREAM, a pipeline for reconstruction and visualization of differentiation trajectories from both single-cell RNA-seq and ATAC-seq data.
format article
author Huidong Chen
Luca Albergante
Jonathan Y. Hsu
Caleb A. Lareau
Giosuè Lo Bosco
Jihong Guan
Shuigeng Zhou
Alexander N. Gorban
Daniel E. Bauer
Martin J. Aryee
David M. Langenau
Andrei Zinovyev
Jason D. Buenrostro
Guo-Cheng Yuan
Luca Pinello
author_facet Huidong Chen
Luca Albergante
Jonathan Y. Hsu
Caleb A. Lareau
Giosuè Lo Bosco
Jihong Guan
Shuigeng Zhou
Alexander N. Gorban
Daniel E. Bauer
Martin J. Aryee
David M. Langenau
Andrei Zinovyev
Jason D. Buenrostro
Guo-Cheng Yuan
Luca Pinello
author_sort Huidong Chen
title Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM
title_short Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM
title_full Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM
title_fullStr Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM
title_full_unstemmed Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM
title_sort single-cell trajectories reconstruction, exploration and mapping of omics data with stream
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/a8fc084be2f940a8842ac27783508d69
work_keys_str_mv AT huidongchen singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT lucaalbergante singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT jonathanyhsu singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT calebalareau singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT giosuelobosco singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT jihongguan singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT shuigengzhou singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT alexanderngorban singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT danielebauer singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT martinjaryee singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT davidmlangenau singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT andreizinovyev singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT jasondbuenrostro singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT guochengyuan singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
AT lucapinello singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream
_version_ 1718382166392438784