Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM
The increasing accessibility of single cell omics technologies beyond transcriptomics demands parallel advances in analysis. Here, the authors introduce STREAM, a pipeline for reconstruction and visualization of differentiation trajectories from both single-cell RNA-seq and ATAC-seq data.
Guardado en:
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/a8fc084be2f940a8842ac27783508d69 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:a8fc084be2f940a8842ac27783508d69 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:a8fc084be2f940a8842ac27783508d692021-12-02T17:01:28ZSingle-cell trajectories reconstruction, exploration and mapping of omics data with STREAM10.1038/s41467-019-09670-42041-1723https://doaj.org/article/a8fc084be2f940a8842ac27783508d692019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09670-4https://doaj.org/toc/2041-1723The increasing accessibility of single cell omics technologies beyond transcriptomics demands parallel advances in analysis. Here, the authors introduce STREAM, a pipeline for reconstruction and visualization of differentiation trajectories from both single-cell RNA-seq and ATAC-seq data.Huidong ChenLuca AlberganteJonathan Y. HsuCaleb A. LareauGiosuè Lo BoscoJihong GuanShuigeng ZhouAlexander N. GorbanDaniel E. BauerMartin J. AryeeDavid M. LangenauAndrei ZinovyevJason D. BuenrostroGuo-Cheng YuanLuca PinelloNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Huidong Chen Luca Albergante Jonathan Y. Hsu Caleb A. Lareau Giosuè Lo Bosco Jihong Guan Shuigeng Zhou Alexander N. Gorban Daniel E. Bauer Martin J. Aryee David M. Langenau Andrei Zinovyev Jason D. Buenrostro Guo-Cheng Yuan Luca Pinello Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM |
description |
The increasing accessibility of single cell omics technologies beyond transcriptomics demands parallel advances in analysis. Here, the authors introduce STREAM, a pipeline for reconstruction and visualization of differentiation trajectories from both single-cell RNA-seq and ATAC-seq data. |
format |
article |
author |
Huidong Chen Luca Albergante Jonathan Y. Hsu Caleb A. Lareau Giosuè Lo Bosco Jihong Guan Shuigeng Zhou Alexander N. Gorban Daniel E. Bauer Martin J. Aryee David M. Langenau Andrei Zinovyev Jason D. Buenrostro Guo-Cheng Yuan Luca Pinello |
author_facet |
Huidong Chen Luca Albergante Jonathan Y. Hsu Caleb A. Lareau Giosuè Lo Bosco Jihong Guan Shuigeng Zhou Alexander N. Gorban Daniel E. Bauer Martin J. Aryee David M. Langenau Andrei Zinovyev Jason D. Buenrostro Guo-Cheng Yuan Luca Pinello |
author_sort |
Huidong Chen |
title |
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM |
title_short |
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM |
title_full |
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM |
title_fullStr |
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM |
title_full_unstemmed |
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM |
title_sort |
single-cell trajectories reconstruction, exploration and mapping of omics data with stream |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/a8fc084be2f940a8842ac27783508d69 |
work_keys_str_mv |
AT huidongchen singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT lucaalbergante singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT jonathanyhsu singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT calebalareau singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT giosuelobosco singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT jihongguan singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT shuigengzhou singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT alexanderngorban singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT danielebauer singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT martinjaryee singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT davidmlangenau singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT andreizinovyev singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT jasondbuenrostro singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT guochengyuan singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream AT lucapinello singlecelltrajectoriesreconstructionexplorationandmappingofomicsdatawithstream |
_version_ |
1718382166392438784 |