RNA-Sequencing data supports the existence of novel VEGFA splicing events but not of VEGFAxxxb isoforms
Abstract Vascular endothelial growth factor (VEGFA), a pivotal regulator of angiogenesis and valuable therapeutic target, is characterised by alternative splicing which generates three principal isoforms, VEGFA121, VEGFA165 and VEGFA189. A second set of anti-angiogenic isoforms termed VEGFAxxxb that...
Enregistré dans:
Auteurs principaux: | Stephen Bridgett, Margaret Dellett, David A. Simpson |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/a903cee8d8004fe48b45ecb0d3a60fde |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Systematically differentiating functions for alternatively spliced isoforms through integrating RNA-seq data.
par: Ridvan Eksi, et autres
Publié: (2013) -
Detection of aberrant splicing events in RNA-seq data using FRASER
par: Christian Mertes, et autres
Publié: (2021) -
Single-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes
par: Chenchen Zhu, et autres
Publié: (2021) -
Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing
par: Szi Kay Leung, et autres
Publié: (2021) -
Computational characterization of 3' splice variants in the GFAP isoform family.
par: Sarah E Boyd, et autres
Publié: (2012)