Continuous learning and inference of individual probability of SARS-CoV-2 infection based on interaction data

Abstract This study presents a new approach to determine the likelihood of asymptomatic carriers of the SARS-CoV-2 virus by using interaction-based continuous learning and inference of individual probability (CLIIP) for contagious ranking. This approach is developed based on an individual directed g...

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Bibliographic Details
Main Authors: Shangching Liu, Koyun Liu, Hwaihai Chiang, Jianwei Zhang, Tsungyao Chang
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/a917d58029a44f128e3e181c6d1f4bdf
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Summary:Abstract This study presents a new approach to determine the likelihood of asymptomatic carriers of the SARS-CoV-2 virus by using interaction-based continuous learning and inference of individual probability (CLIIP) for contagious ranking. This approach is developed based on an individual directed graph (IDG), using multi-layer bidirectional path tracking and inference searching. The IDG is determined by the appearance timeline and spatial data that can adapt over time. Additionally, the approach takes into consideration the incubation period and several features that can represent real-world circumstances, such as the number of asymptomatic carriers present. After each update of confirmed cases, the model collects the interaction features and infers the individual person’s probability of getting infected using the status of the surrounding people. The CLIIP approach is validated using the individualized bidirectional SEIR model to simulate the contagion process. Compared to traditional contact tracing methods, our approach significantly reduces the screening and quarantine required to search for the potential asymptomatic virus carriers by as much as 94%.