Sitagliptin attenuates arterial calcification by downregulating oxidative stress-induced receptor for advanced glycation end products in LDLR knockout mice

QR Code

Sitagliptin attenuates arterial calcification by downregulating oxidative stress-induced receptor for advanced glycation end products in LDLR knockout mice

Abstract Diabetes is a complex disease characterized by hyperglycemia, dyslipidemia, and insulin resistance. Plasma advanced glycation end products (AGEs) activated the receptor for advanced glycation end products (RAGE) and the activation of RAGE is implicated to be the pathogenesis of type 2 diabe...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Chih-Pei Lin, Po-Hsun Huang, Chi-Yu Chen, Meng-Yu Wu, Jia-Shiong Chen, Jaw-Wen Chen, Shing-Jong Lin
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Medicine R Science Q
Accès en ligne:	https://doaj.org/article/a91ccdc0d60a4a68ac60662d9f835fc8
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Fenofibrate attenuates doxorubicin-induced cardiac dysfunction in mice via activating the eNOS/EPC pathway
par: Wen-Pin Huang, et autres
Publié: (2021)

Therapeutic targets of hypercholesterolemia: HMGCR and LDLR
par: Ma S, et autres
Publié: (2019)

Advanced Glycation End-Products in Skeletal Muscle Aging
par: Lucas C. Olson, et autres
Publié: (2021)

The impact of endothelial progenitor cells on restenosis after percutaneous angioplasty of hemodialysis vascular access.
par: Chih-Cheng Wu, et autres
Publié: (2014)

Leptin and advanced glycation end products receptor (RAGE) in tuberculosis patients.
par: Tássia Kirchmann Lazzari, et autres
Publié: (2021)

Fingertip advanced glycation end products and psychotic symptoms among adolescents
par: Mitsuhiro Miyashita, et autres
Publié: (2021)

Formation of advanced glycation end products in raw and subsequently boiled broiler muscle: biological variation and effects of postmortem ageing and storage
par: Suhong Huang, et autres
Publié: (2022)

Prediction of Masked Hypertension and Masked Uncontrolled Hypertension Using Machine Learning
par: Ming-Hui Hung, et autres
Publié: (2021)

Advanced glycation end products and their receptors in serum of patients with type 2 diabetes
par: Diana Indyk, et autres
Publié: (2021)

Inhibition of Advanced Glycation End Products in Yogurt by Lotus Seedpod Oligomeric Procyanidin
par: Nianjie Feng, et autres
Publié: (2021)

SRC-3 Knockout Attenuates Myocardial Injury Induced by Chronic Intermittent Hypoxia in Mice
par: Wanyu Wang, et autres
Publié: (2021)

Autofluorescence as a noninvasive biomarker of senescence and advanced glycation end products in Caenorhabditis elegans
par: Tomomi Komura, et autres
Publié: (2021)

Advanced glycation end products as predictors of renal function in youth with type 1 diabetes
par: Josephine M. Forbes, et autres
Publié: (2021)

Berberine suppresses advanced glycation end products‐associated diabetic retinopathy in hyperglycemic mice
par: Ning Wang, et autres
Publié: (2021)

Inhibitory effect of metformin and pyridoxamine in the formation of early, intermediate and advanced glycation end-products.
par: Saheem Ahmad, et autres
Publié: (2013)

Significance of serum FGF-23 for risk assessment of contrast-associated acute kidney injury and clinical outcomes in patients undergoing coronary angiography.
par: Shao-Sung Huang, et autres
Publié: (2021)

Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr−/−.Leiden mice without attenuation of steatohepatitis
par: Leticia Álvarez-Amor, et autres
Publié: (2021)

Oral supplementation with non-absorbable antibiotics or curcumin attenuates western diet-induced atherosclerosis and glucose intolerance in LDLR-/- mice--role of intestinal permeability and macrophage activation.
par: Siddhartha S Ghosh, et autres
Publié: (2014)

Scavenging of reactive dicarbonyls with 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic Ldlr −/− mice
par: Huan Tao, et autres
Publié: (2020)

Advanced glycation end products in infant formulas do not contribute to insulin resistance associated with their consumption.
par: Kristína Simon Klenovics, et autres
Publié: (2013)

Intestinal transepithelial permeability of oxytocin into the blood is dependent on the receptor for advanced glycation end products in mice
par: Haruhiro Higashida, et autres
Publié: (2017)

ß-arrestin 2 germline knockout does not attenuate opioid respiratory depression
par: Iris Bachmutsky, et autres
Publié: (2021)

Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice.
par: Kia J Jackson, et autres
Publié: (2012)

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL
par: Paulina Bartuzi, et autres
Publié: (2016)

DJ-1 attenuates the glycation of mitochondrial complex I and complex III in the post-ischemic heart
par: Yvanna Pantner, et autres
Publié: (2021)

Quercetin improves lipid metabolism via SCAP-SREBP2-LDLr signaling pathway in early stage diabetic nephropathy
par: Jiang X, et autres
Publié: (2019)

Outcome and cost analysis of primary total knee arthroplasty in end-stage renal disease patients: A nationwide population-based study
par: Sheng-Hsun Lee, et autres
Publié: (2021)

S100A8 inhibits PDGF-induced proliferation of airway smooth muscle cells dependent on the receptor for advanced glycation end-products
par: Xu,Yu‑Dong, et autres
Publié: (2017)

Transthyretin and Receptor for Advanced Glycation End Product’s Differential Levels Associated with the Pathogenesis of Rheumatoid Arthritis
par: Monu, et autres
Publié: (2021)

Current perspectives on the health risks associated with the consumption of advanced glycation end products: recommendations for dietary management
par: Palimeri S, et autres
Publié: (2015)

Comparison of extended release GLP-1 receptor agonist therapy versus sitagliptin in the management of type 2 diabetes
par: Stolar MW, et autres
Publié: (2013)

Sitagliptin as combination therapy in the treatment of type 2 diabetes mellitus
par: Shannon A Miller, et autres
Publié: (2009)

The durability of sitagliptin in elderly patients with type 2 diabetes
par: Hsieh CJ, et autres
Publié: (2014)

Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis
par: Chen-Hsueh Pai, et autres
Publié: (2020)

Oestrogen Inhibits Arterial Calcification by Promoting Autophagy
par: Yi-Qun Peng, et autres
Publié: (2017)

Simvastatin nanoparticles attenuated intestinal ischemia/reperfusion injury by downregulating BMP4/COX-2 pathway in rats
par: Tong F, et autres
Publié: (2017)

The effect of liraglutide and sitagliptin on oxidative stress in persons with type 2 diabetes
par: Suvanjaa Sivalingam, et autres
Publié: (2021)

Use of DPP-4 inhibitors in type 2 diabetes: focus on sitagliptin
par: Bo Ahr&eacute;n
Publié: (2010)

Fixed-dose combination of sitagliptin and metformin for the treatment of type 2 diabetes
par: Jonathan K Reynolds
Publié: (2009)

Use of DPP-4 inhibitors in type 2 diabetes: focus on sitagliptin
par: Ahren B
Publié: (2010)