Thymic homing of activated CD4+ T cells induces degeneration of the thymic epithelium through excessive RANK signaling

Thymic homing of activated CD4+ T cells induces degeneration of the thymic epithelium through excessive RANK signaling

Abstract Activated T cells have been shown to be able to recirculate into the thymus from the periphery. The present study was aimed to elucidate the functional consequences of thymic homing of activated T cells upon developing thymocytes and thymic epithelial cells (TEC). In the presence of activat...

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Autores principales: Chen Yin, Xiao-Yan Pei, Hui Shen, Ya-Nan Gao, Xiu-Yuan Sun, Wei Wang, Qing Ge, Yu Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a91e87881d6f4e9386a58a9691f1b7b7
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