Eradication of unresectable liver metastasis through induction of tumour specific energy depletion

Treatment of liver metastasis in cancer patients is associated with severe side effects. Here, the authors develop nucleus and mitochondria targeted nanoparticles, conjugated via a cathepsin B sensitive peptide to selectively target liver metastatic cells.

Guardado en:
Detalles Bibliográficos
Autores principales: Da Huo, Jianfeng Zhu, Guojun Chen, Qian Chen, Chao Zhang, Xingyu Luo, Wei Jiang, Xiqun Jiang, Zhen Gu, Yong Hu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/a92508a4c97a4fc79acc2c38b0b3d30e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Treatment of liver metastasis in cancer patients is associated with severe side effects. Here, the authors develop nucleus and mitochondria targeted nanoparticles, conjugated via a cathepsin B sensitive peptide to selectively target liver metastatic cells.