Eradication of unresectable liver metastasis through induction of tumour specific energy depletion

Treatment of liver metastasis in cancer patients is associated with severe side effects. Here, the authors develop nucleus and mitochondria targeted nanoparticles, conjugated via a cathepsin B sensitive peptide to selectively target liver metastatic cells.

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Autores principales:	Da Huo, Jianfeng Zhu, Guojun Chen, Qian Chen, Chao Zhang, Xingyu Luo, Wei Jiang, Xiqun Jiang, Zhen Gu, Yong Hu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a92508a4c97a4fc79acc2c38b0b3d30e
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spelling	oai:doaj.org-article:a92508a4c97a4fc79acc2c38b0b3d30e2021-12-02T14:35:51ZEradication of unresectable liver metastasis through induction of tumour specific energy depletion10.1038/s41467-019-11082-32041-1723https://doaj.org/article/a92508a4c97a4fc79acc2c38b0b3d30e2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11082-3https://doaj.org/toc/2041-1723Treatment of liver metastasis in cancer patients is associated with severe side effects. Here, the authors develop nucleus and mitochondria targeted nanoparticles, conjugated via a cathepsin B sensitive peptide to selectively target liver metastatic cells.Da HuoJianfeng ZhuGuojun ChenQian ChenChao ZhangXingyu LuoWei JiangXiqun JiangZhen GuYong HuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Da Huo Jianfeng Zhu Guojun Chen Qian Chen Chao Zhang Xingyu Luo Wei Jiang Xiqun Jiang Zhen Gu Yong Hu Eradication of unresectable liver metastasis through induction of tumour specific energy depletion
description	Treatment of liver metastasis in cancer patients is associated with severe side effects. Here, the authors develop nucleus and mitochondria targeted nanoparticles, conjugated via a cathepsin B sensitive peptide to selectively target liver metastatic cells.
format	article
author	Da Huo Jianfeng Zhu Guojun Chen Qian Chen Chao Zhang Xingyu Luo Wei Jiang Xiqun Jiang Zhen Gu Yong Hu
author_facet	Da Huo Jianfeng Zhu Guojun Chen Qian Chen Chao Zhang Xingyu Luo Wei Jiang Xiqun Jiang Zhen Gu Yong Hu
author_sort	Da Huo
title	Eradication of unresectable liver metastasis through induction of tumour specific energy depletion
title_short	Eradication of unresectable liver metastasis through induction of tumour specific energy depletion
title_full	Eradication of unresectable liver metastasis through induction of tumour specific energy depletion
title_fullStr	Eradication of unresectable liver metastasis through induction of tumour specific energy depletion
title_full_unstemmed	Eradication of unresectable liver metastasis through induction of tumour specific energy depletion
title_sort	eradication of unresectable liver metastasis through induction of tumour specific energy depletion
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/a92508a4c97a4fc79acc2c38b0b3d30e
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Eradication of unresectable liver metastasis through induction of tumour specific energy depletion

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