Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments

Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments

The mechanics of the migration of T cells into tumours is an important aspect of tumour immunity. Here the authors engineer complex 3D environments to explore functions of microtubules and cell contractility as strategies to enhance T cell migration in tumour microenvironments.

Saved in:
Bibliographic Details
Main Authors: Erdem D. Tabdanov, Nelson J. Rodríguez-Merced, Alexander X. Cartagena-Rivera, Vikram V. Puram, Mackenzie K. Callaway, Ethan A. Ensminger, Emily J. Pomeroy, Kenta Yamamoto, Walker S. Lahr, Beau R. Webber, Branden S. Moriarity, Alexander S. Zhovmer, Paolo P. Provenzano
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/a9258c06966543cda042cc7df55119b0
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/a9258c06966543cda042cc7df55119b0

Similar Items