A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells

A prior live-cell exosome reporter showed dim fluorescence and could not be expressed stably, limiting its usefulness. Here the authors stabilise the reporter to allow long-term tracking of exosomes, and incorporate a second fluorophore to visualise the entire exosome lifecycle.

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Autores principales: Bong Hwan Sung, Ariana von Lersner, Jorge Guerrero, Evan S. Krystofiak, David Inman, Roxanne Pelletier, Andries Zijlstra, Suzanne M. Ponik, Alissa M. Weaver
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a92f2f1ca0644dc2b5577af154c973ca
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