The chromatin remodelling factor Chd7 protects auditory neurons and sensory hair cells from stress-induced degeneration

To improve our understanding of the mechanisms that protect hair cells in the ear from stress-induced death, Ahmed et al delete the chromodomain helicase DNA-binding protein 7 (CHD7) in auditory neurons and hair cells in mice. They observe sensorineural hearing loss and demonstrate that CHD7 control...

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Autores principales: Mohi Ahmed, Ruth Moon, Ravindra Singh Prajapati, Elysia James, M. Albert Basson, Andrea Streit
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a92fb875cfc14184bbec21667fb5460f
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