Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age

Skewing of X chromosome inactivation (XCI) occurs when the silencing of one parental X chromosome is non-random. Here, Zito et al. report XCI patterns in lymphoblastoid cell lines, blood, subcutaneous adipose tissue samples and skin samples of monozygotic and dizygotic twins and find XCI skew to ass...

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Autores principales:	Antonino Zito, Matthew N. Davies, Pei-Chien Tsai, Susanna Roberts, Rosa Andres-Ejarque, Stefano Nardone, Jordana T. Bell, Chloe C. Y. Wong, Kerrin S. Small
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a930e629700d41afa50c28ffc5023117
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spelling	oai:doaj.org-article:a930e629700d41afa50c28ffc50231172021-12-02T16:58:05ZHeritability of skewed X-inactivation in female twins is tissue-specific and associated with age10.1038/s41467-019-13340-w2041-1723https://doaj.org/article/a930e629700d41afa50c28ffc50231172019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13340-whttps://doaj.org/toc/2041-1723Skewing of X chromosome inactivation (XCI) occurs when the silencing of one parental X chromosome is non-random. Here, Zito et al. report XCI patterns in lymphoblastoid cell lines, blood, subcutaneous adipose tissue samples and skin samples of monozygotic and dizygotic twins and find XCI skew to associate with tissue and age.Antonino ZitoMatthew N. DaviesPei-Chien TsaiSusanna RobertsRosa Andres-EjarqueStefano NardoneJordana T. BellChloe C. Y. WongKerrin S. SmallNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Antonino Zito Matthew N. Davies Pei-Chien Tsai Susanna Roberts Rosa Andres-Ejarque Stefano Nardone Jordana T. Bell Chloe C. Y. Wong Kerrin S. Small Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age
description	Skewing of X chromosome inactivation (XCI) occurs when the silencing of one parental X chromosome is non-random. Here, Zito et al. report XCI patterns in lymphoblastoid cell lines, blood, subcutaneous adipose tissue samples and skin samples of monozygotic and dizygotic twins and find XCI skew to associate with tissue and age.
format	article
author	Antonino Zito Matthew N. Davies Pei-Chien Tsai Susanna Roberts Rosa Andres-Ejarque Stefano Nardone Jordana T. Bell Chloe C. Y. Wong Kerrin S. Small
author_facet	Antonino Zito Matthew N. Davies Pei-Chien Tsai Susanna Roberts Rosa Andres-Ejarque Stefano Nardone Jordana T. Bell Chloe C. Y. Wong Kerrin S. Small
author_sort	Antonino Zito
title	Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age
title_short	Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age
title_full	Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age
title_fullStr	Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age
title_full_unstemmed	Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age
title_sort	heritability of skewed x-inactivation in female twins is tissue-specific and associated with age
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/a930e629700d41afa50c28ffc5023117
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Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age

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