The origin of a primordial genome through spontaneous symmetry breaking

Early molecules of life likely served both as templates and catalysts, raising the question of how functionally distinct genomes and enzymes arose. Here, the authors show that conflict between evolution at the molecular and cellular levels can drive functional differentiation of the two strands of s...

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Autores principales:	Nobuto Takeuchi, Paulien Hogeweg, Kunihiko Kaneko
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a9324f8d29434b11b4e65ca140215cea
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spelling	oai:doaj.org-article:a9324f8d29434b11b4e65ca140215cea2021-12-02T14:16:05ZThe origin of a primordial genome through spontaneous symmetry breaking10.1038/s41467-017-00243-x2041-1723https://doaj.org/article/a9324f8d29434b11b4e65ca140215cea2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00243-xhttps://doaj.org/toc/2041-1723Early molecules of life likely served both as templates and catalysts, raising the question of how functionally distinct genomes and enzymes arose. Here, the authors show that conflict between evolution at the molecular and cellular levels can drive functional differentiation of the two strands of self-replicating molecules and lead to copy number differences between the two.Nobuto TakeuchiPaulien HogewegKunihiko KanekoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nobuto Takeuchi Paulien Hogeweg Kunihiko Kaneko The origin of a primordial genome through spontaneous symmetry breaking
description	Early molecules of life likely served both as templates and catalysts, raising the question of how functionally distinct genomes and enzymes arose. Here, the authors show that conflict between evolution at the molecular and cellular levels can drive functional differentiation of the two strands of self-replicating molecules and lead to copy number differences between the two.
format	article
author	Nobuto Takeuchi Paulien Hogeweg Kunihiko Kaneko
author_facet	Nobuto Takeuchi Paulien Hogeweg Kunihiko Kaneko
author_sort	Nobuto Takeuchi
title	The origin of a primordial genome through spontaneous symmetry breaking
title_short	The origin of a primordial genome through spontaneous symmetry breaking
title_full	The origin of a primordial genome through spontaneous symmetry breaking
title_fullStr	The origin of a primordial genome through spontaneous symmetry breaking
title_full_unstemmed	The origin of a primordial genome through spontaneous symmetry breaking
title_sort	origin of a primordial genome through spontaneous symmetry breaking
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/a9324f8d29434b11b4e65ca140215cea
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The origin of a primordial genome through spontaneous symmetry breaking

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