Chemogenomic Screen for Imipenem Resistance in Gram-Negative Bacteria

ABSTRACT Carbapenem-resistant Gram-negative bacteria are considered a major threat to global health. Imipenem (IMP) is used as a last line of treatment against these pathogens, but its efficacy is diminished by the emergence of resistance. We applied a whole-genome screen in Escherichia coli, Klebsi...

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Bibliographic Details
Main Authors: Jessica Y. El Khoury, Alexandra Maure, Hélène Gingras, Philippe Leprohon, Marc Ouellette
Format: article
Language:EN
Published: American Society for Microbiology 2019
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Online Access:https://doaj.org/article/a933a8c7d8e94f08abc8a8366fe32f0a
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