Chemogenomic Screen for Imipenem Resistance in Gram-Negative Bacteria
ABSTRACT Carbapenem-resistant Gram-negative bacteria are considered a major threat to global health. Imipenem (IMP) is used as a last line of treatment against these pathogens, but its efficacy is diminished by the emergence of resistance. We applied a whole-genome screen in Escherichia coli, Klebsi...
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Main Authors: | Jessica Y. El Khoury, Alexandra Maure, Hélène Gingras, Philippe Leprohon, Marc Ouellette |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2019
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Online Access: | https://doaj.org/article/a933a8c7d8e94f08abc8a8366fe32f0a |
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