Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males
Selfish DNA such as transposable elements cause intragenomic conflict. This study finds that on an evolutionarily young, gene-rich Drosophila Y chromosome, transposable elements evade heterochromatic suppression, leading to elevated transposition rates in males.
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Nature Portfolio
2020
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oai:doaj.org-article:a93c29582b0e4890bcc55fb2eea7252f2021-12-02T14:42:49ZEpigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males10.1038/s41467-020-19134-92041-1723https://doaj.org/article/a93c29582b0e4890bcc55fb2eea7252f2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19134-9https://doaj.org/toc/2041-1723Selfish DNA such as transposable elements cause intragenomic conflict. This study finds that on an evolutionarily young, gene-rich Drosophila Y chromosome, transposable elements evade heterochromatic suppression, leading to elevated transposition rates in males.Kevin H.-C. WeiLauren GibiliscoDoris BachtrogNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020) |
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Science Q Kevin H.-C. Wei Lauren Gibilisco Doris Bachtrog Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males |
description |
Selfish DNA such as transposable elements cause intragenomic conflict. This study finds that on an evolutionarily young, gene-rich Drosophila Y chromosome, transposable elements evade heterochromatic suppression, leading to elevated transposition rates in males. |
format |
article |
author |
Kevin H.-C. Wei Lauren Gibilisco Doris Bachtrog |
author_facet |
Kevin H.-C. Wei Lauren Gibilisco Doris Bachtrog |
author_sort |
Kevin H.-C. Wei |
title |
Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males |
title_short |
Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males |
title_full |
Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males |
title_fullStr |
Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males |
title_full_unstemmed |
Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males |
title_sort |
epigenetic conflict on a degenerating y chromosome increases mutational burden in drosophila males |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/a93c29582b0e4890bcc55fb2eea7252f |
work_keys_str_mv |
AT kevinhcwei epigeneticconflictonadegeneratingychromosomeincreasesmutationalburdenindrosophilamales AT laurengibilisco epigeneticconflictonadegeneratingychromosomeincreasesmutationalburdenindrosophilamales AT dorisbachtrog epigeneticconflictonadegeneratingychromosomeincreasesmutationalburdenindrosophilamales |
_version_ |
1718389588168278016 |