Prospects and limitations of physiologically-based pharmacokinetic modelling for cross-species extrapolation
The transition from experimental findings in animal models to clinical applications in human patients is a key challenge in pharmacology and toxicology. To date, this step still inhibits a significant level of uncertainty explaining amongst others the continuously high attrition rates in pharmace...
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| Formato: | article |
| Lenguaje: | EN |
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South Valley University
2019
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| Acceso en línea: | https://doaj.org/article/a94188f39ce3415882c79a550fba59d8 |
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