Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils

Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils

Abstract CarD is an essential global transcription regulator from Mycobacterium tuberculosis (Mtb) that binds RNA polymerase and activates transcription by stabilizing the transcription initiation complex. Available crystal structures have captured two distinct, monomeric and domain-swapped homodime...

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Autores principales: Gundeep Kaur, Soni Kaundal, Srajan Kapoor, Jonathan M. Grimes, Juha T. Huiskonen, Krishan Gopal Thakur
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/a9492ed5026b4972a6e8434e695cc730
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