Larvicidal and ovicidal activities of Artocarpus blancoi extracts against Aedes aegypti

Context: Dengue control may be done by targeting its vector. In this study, we used Artocarpus blancoi (Elm.) Merr. (Moraceae) leaves, an endemic hematophagous insect repellent as a larvicide and ovicide. Objective: We investigated the larvicidal and ovicidal activities of its soluble crude ethanol...

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Autores principales: Maria Ruth B. Pineda-Cortel, Rachel Joy R. Cabantog, Paulo M. Caasi, Charles Anson D. Ching, Joseph Benjamin S. Perez, Paulo Gabriel M. Godisan, Cheska Marie G. Latorre, Danielle R. Lucero, Reginald B. Salonga
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Publicado: Taylor & Francis Group 2019
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spelling oai:doaj.org-article:a94c908bbae5470e9c75715b0c0e7e382021-11-17T14:21:55ZLarvicidal and ovicidal activities of Artocarpus blancoi extracts against Aedes aegypti1388-02091744-511610.1080/13880209.2018.1561727https://doaj.org/article/a94c908bbae5470e9c75715b0c0e7e382019-01-01T00:00:00Zhttp://dx.doi.org/10.1080/13880209.2018.1561727https://doaj.org/toc/1388-0209https://doaj.org/toc/1744-5116Context: Dengue control may be done by targeting its vector. In this study, we used Artocarpus blancoi (Elm.) Merr. (Moraceae) leaves, an endemic hematophagous insect repellent as a larvicide and ovicide. Objective: We investigated the larvicidal and ovicidal activities of its soluble crude ethanol extract and the hexane, aqueous, and ethyl acetate fractions against Aedes aegypti. Materials and methods: Third to early fourth instar A. aegypti larvae were exposed to 200, 400, 600, 800 and 1000 ppm of crude ethanol; to 10, 20, 40, 60 and 80 ppm of ethyl acetate; and to 500, 750, 1000, 1250 and 1500 ppm of hexane fractions of A. blancoi; 48 h LC50 and LC90 values were determined. For the ovicidal assay, an average of 25 eggs/paper strip was used; inhibition of egg hatchability was counted 72 h after exposure. Fractions were screened qualitatively for phytochemicals. Results: Ethyl acetate soluble fraction gave the lowest LC50 value (18.59 ppm) followed by the crude ethanol (411 ppm), hexane (685 ppm) and aqueous (20,158 ppm) fractions. Similarly, ethyl acetate soluble fraction appeared to be the most ovicidal (80 ppm). Larvicidal and ovicidal activities of the fractions were dose dependent. Qualitative phytochemical screening revealed moderate presence of glycosides and sterols and trace amounts of triterpenes, flavonoids, saponins and tannins. Discussion and conclusions: A. blancoi is a potential larvicide and ovicide against A. aegypti, and future studies isolating the specific components responsible for such actions would be significant.Maria Ruth B. Pineda-CortelRachel Joy R. CabantogPaulo M. CaasiCharles Anson D. ChingJoseph Benjamin S. PerezPaulo Gabriel M. GodisanCheska Marie G. LatorreDanielle R. LuceroReginald B. SalongaTaylor & Francis Grouparticledenguemosquitovector bornephilippinespreventionphytochemicalTherapeutics. PharmacologyRM1-950ENPharmaceutical Biology, Vol 57, Iss 1, Pp 120-124 (2019)
institution DOAJ
collection DOAJ
language EN
topic dengue
mosquito
vector borne
philippines
prevention
phytochemical
Therapeutics. Pharmacology
RM1-950
spellingShingle dengue
mosquito
vector borne
philippines
prevention
phytochemical
Therapeutics. Pharmacology
RM1-950
Maria Ruth B. Pineda-Cortel
Rachel Joy R. Cabantog
Paulo M. Caasi
Charles Anson D. Ching
Joseph Benjamin S. Perez
Paulo Gabriel M. Godisan
Cheska Marie G. Latorre
Danielle R. Lucero
Reginald B. Salonga
Larvicidal and ovicidal activities of Artocarpus blancoi extracts against Aedes aegypti
description Context: Dengue control may be done by targeting its vector. In this study, we used Artocarpus blancoi (Elm.) Merr. (Moraceae) leaves, an endemic hematophagous insect repellent as a larvicide and ovicide. Objective: We investigated the larvicidal and ovicidal activities of its soluble crude ethanol extract and the hexane, aqueous, and ethyl acetate fractions against Aedes aegypti. Materials and methods: Third to early fourth instar A. aegypti larvae were exposed to 200, 400, 600, 800 and 1000 ppm of crude ethanol; to 10, 20, 40, 60 and 80 ppm of ethyl acetate; and to 500, 750, 1000, 1250 and 1500 ppm of hexane fractions of A. blancoi; 48 h LC50 and LC90 values were determined. For the ovicidal assay, an average of 25 eggs/paper strip was used; inhibition of egg hatchability was counted 72 h after exposure. Fractions were screened qualitatively for phytochemicals. Results: Ethyl acetate soluble fraction gave the lowest LC50 value (18.59 ppm) followed by the crude ethanol (411 ppm), hexane (685 ppm) and aqueous (20,158 ppm) fractions. Similarly, ethyl acetate soluble fraction appeared to be the most ovicidal (80 ppm). Larvicidal and ovicidal activities of the fractions were dose dependent. Qualitative phytochemical screening revealed moderate presence of glycosides and sterols and trace amounts of triterpenes, flavonoids, saponins and tannins. Discussion and conclusions: A. blancoi is a potential larvicide and ovicide against A. aegypti, and future studies isolating the specific components responsible for such actions would be significant.
format article
author Maria Ruth B. Pineda-Cortel
Rachel Joy R. Cabantog
Paulo M. Caasi
Charles Anson D. Ching
Joseph Benjamin S. Perez
Paulo Gabriel M. Godisan
Cheska Marie G. Latorre
Danielle R. Lucero
Reginald B. Salonga
author_facet Maria Ruth B. Pineda-Cortel
Rachel Joy R. Cabantog
Paulo M. Caasi
Charles Anson D. Ching
Joseph Benjamin S. Perez
Paulo Gabriel M. Godisan
Cheska Marie G. Latorre
Danielle R. Lucero
Reginald B. Salonga
author_sort Maria Ruth B. Pineda-Cortel
title Larvicidal and ovicidal activities of Artocarpus blancoi extracts against Aedes aegypti
title_short Larvicidal and ovicidal activities of Artocarpus blancoi extracts against Aedes aegypti
title_full Larvicidal and ovicidal activities of Artocarpus blancoi extracts against Aedes aegypti
title_fullStr Larvicidal and ovicidal activities of Artocarpus blancoi extracts against Aedes aegypti
title_full_unstemmed Larvicidal and ovicidal activities of Artocarpus blancoi extracts against Aedes aegypti
title_sort larvicidal and ovicidal activities of artocarpus blancoi extracts against aedes aegypti
publisher Taylor & Francis Group
publishDate 2019
url https://doaj.org/article/a94c908bbae5470e9c75715b0c0e7e38
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