Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth
Changes in body mass index (BMI) during infancy and childhood follow a well-characterized pattern. Here, Helgeland et al. perform genome-wide association studies for BMI at 12 time points between birth and 8 years of age and find transient associations at the LEP and LEPR loci.
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Nature Portfolio
2019
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oai:doaj.org-article:a952b58378d642d38501928b8cd55d442021-12-02T14:40:19ZGenome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth10.1038/s41467-019-12308-02041-1723https://doaj.org/article/a952b58378d642d38501928b8cd55d442019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12308-0https://doaj.org/toc/2041-1723Changes in body mass index (BMI) during infancy and childhood follow a well-characterized pattern. Here, Helgeland et al. perform genome-wide association studies for BMI at 12 time points between birth and 8 years of age and find transient associations at the LEP and LEPR loci.Øyvind HelgelandMarc VaudelPetur B. JuliussonOddgeir Lingaas HolmenJulius JuodakisJonas BacelisBo JacobssonHaakon LindekleivKristian HveemRolv Terje LieGun Peggy KnudsenCamilla StoltenbergPer MagnusJørn V. SagenAnders MolvenStefan JohanssonPål Rasmus NjølstadNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
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Science Q Øyvind Helgeland Marc Vaudel Petur B. Juliusson Oddgeir Lingaas Holmen Julius Juodakis Jonas Bacelis Bo Jacobsson Haakon Lindekleiv Kristian Hveem Rolv Terje Lie Gun Peggy Knudsen Camilla Stoltenberg Per Magnus Jørn V. Sagen Anders Molven Stefan Johansson Pål Rasmus Njølstad Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth |
description |
Changes in body mass index (BMI) during infancy and childhood follow a well-characterized pattern. Here, Helgeland et al. perform genome-wide association studies for BMI at 12 time points between birth and 8 years of age and find transient associations at the LEP and LEPR loci. |
format |
article |
author |
Øyvind Helgeland Marc Vaudel Petur B. Juliusson Oddgeir Lingaas Holmen Julius Juodakis Jonas Bacelis Bo Jacobsson Haakon Lindekleiv Kristian Hveem Rolv Terje Lie Gun Peggy Knudsen Camilla Stoltenberg Per Magnus Jørn V. Sagen Anders Molven Stefan Johansson Pål Rasmus Njølstad |
author_facet |
Øyvind Helgeland Marc Vaudel Petur B. Juliusson Oddgeir Lingaas Holmen Julius Juodakis Jonas Bacelis Bo Jacobsson Haakon Lindekleiv Kristian Hveem Rolv Terje Lie Gun Peggy Knudsen Camilla Stoltenberg Per Magnus Jørn V. Sagen Anders Molven Stefan Johansson Pål Rasmus Njølstad |
author_sort |
Øyvind Helgeland |
title |
Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth |
title_short |
Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth |
title_full |
Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth |
title_fullStr |
Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth |
title_full_unstemmed |
Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth |
title_sort |
genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/a952b58378d642d38501928b8cd55d44 |
work_keys_str_mv |
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1718390316441010176 |