Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth

Changes in body mass index (BMI) during infancy and childhood follow a well-characterized pattern. Here, Helgeland et al. perform genome-wide association studies for BMI at 12 time points between birth and 8 years of age and find transient associations at the LEP and LEPR loci.

Guardado en:
Detalles Bibliográficos
Autores principales: Øyvind Helgeland, Marc Vaudel, Petur B. Juliusson, Oddgeir Lingaas Holmen, Julius Juodakis, Jonas Bacelis, Bo Jacobsson, Haakon Lindekleiv, Kristian Hveem, Rolv Terje Lie, Gun Peggy Knudsen, Camilla Stoltenberg, Per Magnus, Jørn V. Sagen, Anders Molven, Stefan Johansson, Pål Rasmus Njølstad
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/a952b58378d642d38501928b8cd55d44
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:a952b58378d642d38501928b8cd55d44
record_format dspace
spelling oai:doaj.org-article:a952b58378d642d38501928b8cd55d442021-12-02T14:40:19ZGenome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth10.1038/s41467-019-12308-02041-1723https://doaj.org/article/a952b58378d642d38501928b8cd55d442019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12308-0https://doaj.org/toc/2041-1723Changes in body mass index (BMI) during infancy and childhood follow a well-characterized pattern. Here, Helgeland et al. perform genome-wide association studies for BMI at 12 time points between birth and 8 years of age and find transient associations at the LEP and LEPR loci.Øyvind HelgelandMarc VaudelPetur B. JuliussonOddgeir Lingaas HolmenJulius JuodakisJonas BacelisBo JacobssonHaakon LindekleivKristian HveemRolv Terje LieGun Peggy KnudsenCamilla StoltenbergPer MagnusJørn V. SagenAnders MolvenStefan JohanssonPål Rasmus NjølstadNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Øyvind Helgeland
Marc Vaudel
Petur B. Juliusson
Oddgeir Lingaas Holmen
Julius Juodakis
Jonas Bacelis
Bo Jacobsson
Haakon Lindekleiv
Kristian Hveem
Rolv Terje Lie
Gun Peggy Knudsen
Camilla Stoltenberg
Per Magnus
Jørn V. Sagen
Anders Molven
Stefan Johansson
Pål Rasmus Njølstad
Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth
description Changes in body mass index (BMI) during infancy and childhood follow a well-characterized pattern. Here, Helgeland et al. perform genome-wide association studies for BMI at 12 time points between birth and 8 years of age and find transient associations at the LEP and LEPR loci.
format article
author Øyvind Helgeland
Marc Vaudel
Petur B. Juliusson
Oddgeir Lingaas Holmen
Julius Juodakis
Jonas Bacelis
Bo Jacobsson
Haakon Lindekleiv
Kristian Hveem
Rolv Terje Lie
Gun Peggy Knudsen
Camilla Stoltenberg
Per Magnus
Jørn V. Sagen
Anders Molven
Stefan Johansson
Pål Rasmus Njølstad
author_facet Øyvind Helgeland
Marc Vaudel
Petur B. Juliusson
Oddgeir Lingaas Holmen
Julius Juodakis
Jonas Bacelis
Bo Jacobsson
Haakon Lindekleiv
Kristian Hveem
Rolv Terje Lie
Gun Peggy Knudsen
Camilla Stoltenberg
Per Magnus
Jørn V. Sagen
Anders Molven
Stefan Johansson
Pål Rasmus Njølstad
author_sort Øyvind Helgeland
title Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth
title_short Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth
title_full Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth
title_fullStr Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth
title_full_unstemmed Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth
title_sort genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/a952b58378d642d38501928b8cd55d44
work_keys_str_mv AT øyvindhelgeland genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT marcvaudel genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT peturbjuliusson genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT oddgeirlingaasholmen genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT juliusjuodakis genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT jonasbacelis genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT bojacobsson genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT haakonlindekleiv genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT kristianhveem genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT rolvterjelie genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT gunpeggyknudsen genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT camillastoltenberg genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT permagnus genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT jørnvsagen genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT andersmolven genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT stefanjohansson genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
AT palrasmusnjølstad genomewideassociationstudyrevealsdynamicroleofgeneticvariationininfantandearlychildhoodgrowth
_version_ 1718390316441010176