The metabolic impact of small intestinal nutrient sensing

The gastrointestinal tract participates in maintaining metabolic homeostasis in part through nutrient-sensing and subsequent gut-brain signalling. Here the authors review the role of small intestinal nutrient-sensing in regulation of energy intake and systemic glucose metabolism, and link high-fat d...

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Autores principales: Frank A. Duca, T. M. Zaved Waise, Willem T. Peppler, Tony K. T. Lam
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a95c8ae22f0042f1b3ef962d4051972d
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spelling oai:doaj.org-article:a95c8ae22f0042f1b3ef962d4051972d2021-12-02T14:10:57ZThe metabolic impact of small intestinal nutrient sensing10.1038/s41467-021-21235-y2041-1723https://doaj.org/article/a95c8ae22f0042f1b3ef962d4051972d2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21235-yhttps://doaj.org/toc/2041-1723The gastrointestinal tract participates in maintaining metabolic homeostasis in part through nutrient-sensing and subsequent gut-brain signalling. Here the authors review the role of small intestinal nutrient-sensing in regulation of energy intake and systemic glucose metabolism, and link high-fat diet, obesity and diabetes with perturbations in these pathways.Frank A. DucaT. M. Zaved WaiseWillem T. PepplerTony K. T. LamNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Frank A. Duca
T. M. Zaved Waise
Willem T. Peppler
Tony K. T. Lam
The metabolic impact of small intestinal nutrient sensing
description The gastrointestinal tract participates in maintaining metabolic homeostasis in part through nutrient-sensing and subsequent gut-brain signalling. Here the authors review the role of small intestinal nutrient-sensing in regulation of energy intake and systemic glucose metabolism, and link high-fat diet, obesity and diabetes with perturbations in these pathways.
format article
author Frank A. Duca
T. M. Zaved Waise
Willem T. Peppler
Tony K. T. Lam
author_facet Frank A. Duca
T. M. Zaved Waise
Willem T. Peppler
Tony K. T. Lam
author_sort Frank A. Duca
title The metabolic impact of small intestinal nutrient sensing
title_short The metabolic impact of small intestinal nutrient sensing
title_full The metabolic impact of small intestinal nutrient sensing
title_fullStr The metabolic impact of small intestinal nutrient sensing
title_full_unstemmed The metabolic impact of small intestinal nutrient sensing
title_sort metabolic impact of small intestinal nutrient sensing
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a95c8ae22f0042f1b3ef962d4051972d
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