Determination of the endothelin-1 recognition sites of endothelin receptor type A by the directed-degeneration method
Abstract G-protein coupled receptors (GPCRs) play indispensable physiological roles in cell proliferation, differentiation, and migration; therefore, identifying the mechanisms by which ligands bind to GPCRs is crucial for developing GPCR-targeting pharmaceutics and for understanding critical biolog...
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Autores principales: | Seong-Gu Han, Sanghwan Ko, Won-Kyu Lee, Sang Taek Jung, Yeon Gyu Yu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/a95ef854682540e9ad103939b8dbf401 |
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