Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers

The humoral immune response to SARS-CoV-2 infection is not yet fully understood. Here, Marot et al. monitor the longitudinal profile and neutralizing activity of IgG, IgA, and IgM among 26 healthcare workers and provide evidence for a short-lasting humoral immune protection due to a decrease of neut...

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Autores principales: Stéphane Marot, Isabelle Malet, Valentin Leducq, Karen Zafilaza, Delphine Sterlin, Delphine Planas, Adélie Gothland, Aude Jary, Karim Dorgham, Timothée Bruel, the Sorbonne Université SARS-CoV-2 Neutralizing Antibodies Study Group, Sonia Burrel, David Boutolleau, Olivier Schwartz, Guy Gorochov, Vincent Calvez, Anne-Geneviève Marcelin
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a9638b93fe0e4ec981cfb0e059d4f0d2
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spelling oai:doaj.org-article:a9638b93fe0e4ec981cfb0e059d4f0d22021-12-02T13:30:25ZRapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers10.1038/s41467-021-21111-92041-1723https://doaj.org/article/a9638b93fe0e4ec981cfb0e059d4f0d22021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21111-9https://doaj.org/toc/2041-1723The humoral immune response to SARS-CoV-2 infection is not yet fully understood. Here, Marot et al. monitor the longitudinal profile and neutralizing activity of IgG, IgA, and IgM among 26 healthcare workers and provide evidence for a short-lasting humoral immune protection due to a decrease of neutralizing antibody titers within 3 months.Stéphane MarotIsabelle MaletValentin LeducqKaren ZafilazaDelphine SterlinDelphine PlanasAdélie GothlandAude JaryKarim DorghamTimothée Bruelthe Sorbonne Université SARS-CoV-2 Neutralizing Antibodies Study GroupSonia BurrelDavid BoutolleauOlivier SchwartzGuy GorochovVincent CalvezAnne-Geneviève MarcelinNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stéphane Marot
Isabelle Malet
Valentin Leducq
Karen Zafilaza
Delphine Sterlin
Delphine Planas
Adélie Gothland
Aude Jary
Karim Dorgham
Timothée Bruel
the Sorbonne Université SARS-CoV-2 Neutralizing Antibodies Study Group
Sonia Burrel
David Boutolleau
Olivier Schwartz
Guy Gorochov
Vincent Calvez
Anne-Geneviève Marcelin
Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers
description The humoral immune response to SARS-CoV-2 infection is not yet fully understood. Here, Marot et al. monitor the longitudinal profile and neutralizing activity of IgG, IgA, and IgM among 26 healthcare workers and provide evidence for a short-lasting humoral immune protection due to a decrease of neutralizing antibody titers within 3 months.
format article
author Stéphane Marot
Isabelle Malet
Valentin Leducq
Karen Zafilaza
Delphine Sterlin
Delphine Planas
Adélie Gothland
Aude Jary
Karim Dorgham
Timothée Bruel
the Sorbonne Université SARS-CoV-2 Neutralizing Antibodies Study Group
Sonia Burrel
David Boutolleau
Olivier Schwartz
Guy Gorochov
Vincent Calvez
Anne-Geneviève Marcelin
author_facet Stéphane Marot
Isabelle Malet
Valentin Leducq
Karen Zafilaza
Delphine Sterlin
Delphine Planas
Adélie Gothland
Aude Jary
Karim Dorgham
Timothée Bruel
the Sorbonne Université SARS-CoV-2 Neutralizing Antibodies Study Group
Sonia Burrel
David Boutolleau
Olivier Schwartz
Guy Gorochov
Vincent Calvez
Anne-Geneviève Marcelin
author_sort Stéphane Marot
title Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers
title_short Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers
title_full Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers
title_fullStr Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers
title_full_unstemmed Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers
title_sort rapid decline of neutralizing antibodies against sars-cov-2 among infected healthcare workers
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a9638b93fe0e4ec981cfb0e059d4f0d2
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