CORRELATION OF AGE WITH CENTRAL CORNEAL THICKNESS AND CORNEAL ENDTHELIAL CELL DENSITY IN PAKISTANI POPULATION

Objective: Correlation of age with central corneal thickness (CCT) and corneal endothelial cell density (ECD) in Pakistani population. Study Design: Descriptive cross sectional study. Place and Duration of Study: Armed Forces Institute of Ophthalmology Rawalpindi from Apr 2016 to Oct 2016....

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Autores principales:	Bilal Hassan, Muhammad Tauseef Dildar, Farooq Hyder, Shafaq Rabbani, Asim Mehboob, Muhammad Asad Farooq
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2018
Materias:	age-related changes central corneal thickness Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/a966023a8eca4124a235c779e8163205
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spelling	oai:doaj.org-article:a966023a8eca4124a235c779e81632052021-11-30T02:49:51ZCORRELATION OF AGE WITH CENTRAL CORNEAL THICKNESS AND CORNEAL ENDTHELIAL CELL DENSITY IN PAKISTANI POPULATION0030-96482411-8842https://doaj.org/article/a966023a8eca4124a235c779e81632052018-12-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2595/2117https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: Correlation of age with central corneal thickness (CCT) and corneal endothelial cell density (ECD) in Pakistani population. Study Design: Descriptive cross sectional study. Place and Duration of Study: Armed Forces Institute of Ophthalmology Rawalpindi from Apr 2016 to Oct 2016. Material and Methods: CCT and ECD was measured in 330 eyes of 165 patients, aged between 21-70 years of age. Patients were further divided into five age groups. Three readings were taken for each eye, and mean of three readings was used for the analysis. Pearson correlation was calculated between CCT, ECD and age. Results: A total of 330 eyes of 165 patients were studied. Out of study population, 81 (49.09%) were males and 84 (50.90%) were females. Mean ECD (cell/mm2) was 3063.85 ± 234.65 cells/mm2 and 256.42 ± 475.06 cells/mm2 in patients aged 21–30 years, and 61–70 years respectively. Mean CCT (μm) was 544 ± 18 μm and 528 ±21 μm in patients aged 21–30 years, and 61–70 years respectively. A statistically significant inverse correlation was observed between age and corneal ECD (r=−0.718, p<0.01) and age and CCT (r=−0.230, p<0.01). Conclusion: Both CCT and corneal ECD decrease significantly with age in Pakistani population, with statistically more decrease in ECD with age, than CCT.Bilal HassanMuhammad Tauseef DildarFarooq HyderShafaq RabbaniAsim MehboobMuhammad Asad FarooqArmy Medical College Rawalpindiarticleage-related changescentral corneal thicknessMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 68, Iss 6, Pp 1720-1724 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	age-related changes central corneal thickness Medicine R Medicine (General) R5-920
spellingShingle	age-related changes central corneal thickness Medicine R Medicine (General) R5-920 Bilal Hassan Muhammad Tauseef Dildar Farooq Hyder Shafaq Rabbani Asim Mehboob Muhammad Asad Farooq CORRELATION OF AGE WITH CENTRAL CORNEAL THICKNESS AND CORNEAL ENDTHELIAL CELL DENSITY IN PAKISTANI POPULATION
description	Objective: Correlation of age with central corneal thickness (CCT) and corneal endothelial cell density (ECD) in Pakistani population. Study Design: Descriptive cross sectional study. Place and Duration of Study: Armed Forces Institute of Ophthalmology Rawalpindi from Apr 2016 to Oct 2016. Material and Methods: CCT and ECD was measured in 330 eyes of 165 patients, aged between 21-70 years of age. Patients were further divided into five age groups. Three readings were taken for each eye, and mean of three readings was used for the analysis. Pearson correlation was calculated between CCT, ECD and age. Results: A total of 330 eyes of 165 patients were studied. Out of study population, 81 (49.09%) were males and 84 (50.90%) were females. Mean ECD (cell/mm2) was 3063.85 ± 234.65 cells/mm2 and 256.42 ± 475.06 cells/mm2 in patients aged 21–30 years, and 61–70 years respectively. Mean CCT (μm) was 544 ± 18 μm and 528 ±21 μm in patients aged 21–30 years, and 61–70 years respectively. A statistically significant inverse correlation was observed between age and corneal ECD (r=−0.718, p<0.01) and age and CCT (r=−0.230, p<0.01). Conclusion: Both CCT and corneal ECD decrease significantly with age in Pakistani population, with statistically more decrease in ECD with age, than CCT.
format	article
author	Bilal Hassan Muhammad Tauseef Dildar Farooq Hyder Shafaq Rabbani Asim Mehboob Muhammad Asad Farooq
author_facet	Bilal Hassan Muhammad Tauseef Dildar Farooq Hyder Shafaq Rabbani Asim Mehboob Muhammad Asad Farooq
author_sort	Bilal Hassan
title	CORRELATION OF AGE WITH CENTRAL CORNEAL THICKNESS AND CORNEAL ENDTHELIAL CELL DENSITY IN PAKISTANI POPULATION
title_short	CORRELATION OF AGE WITH CENTRAL CORNEAL THICKNESS AND CORNEAL ENDTHELIAL CELL DENSITY IN PAKISTANI POPULATION
title_full	CORRELATION OF AGE WITH CENTRAL CORNEAL THICKNESS AND CORNEAL ENDTHELIAL CELL DENSITY IN PAKISTANI POPULATION
title_fullStr	CORRELATION OF AGE WITH CENTRAL CORNEAL THICKNESS AND CORNEAL ENDTHELIAL CELL DENSITY IN PAKISTANI POPULATION
title_full_unstemmed	CORRELATION OF AGE WITH CENTRAL CORNEAL THICKNESS AND CORNEAL ENDTHELIAL CELL DENSITY IN PAKISTANI POPULATION
title_sort	correlation of age with central corneal thickness and corneal endthelial cell density in pakistani population
publisher	Army Medical College Rawalpindi
publishDate	2018
url	https://doaj.org/article/a966023a8eca4124a235c779e8163205
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CORRELATION OF AGE WITH CENTRAL CORNEAL THICKNESS AND CORNEAL ENDTHELIAL CELL DENSITY IN PAKISTANI POPULATION

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