The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis

Hitz et al. describe the role of the protein kinase PfCK2α in the development of the human malaria parasite Plasmodium falciparum. Using mutant parasites, they show that PfCK2α is not only essential for asexual but also sexual development of P. falciparum blood stage parasites, and hence it may hold...

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Autores principales:	Eva Hitz, Olivia Grüninger, Armin Passecker, Matthias Wyss, Christian Scheurer, Sergio Wittlin, Hans-Peter Beck, Nicolas M. B. Brancucci, Till S. Voss
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/a968a781e2a9433ca72783a35e1bac0a
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spelling	oai:doaj.org-article:a968a781e2a9433ca72783a35e1bac0a2021-12-02T13:15:51ZThe catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis10.1038/s42003-021-01873-02399-3642https://doaj.org/article/a968a781e2a9433ca72783a35e1bac0a2021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01873-0https://doaj.org/toc/2399-3642Hitz et al. describe the role of the protein kinase PfCK2α in the development of the human malaria parasite Plasmodium falciparum. Using mutant parasites, they show that PfCK2α is not only essential for asexual but also sexual development of P. falciparum blood stage parasites, and hence it may hold promise as a potential target for antimalarial drugs.Eva HitzOlivia GrüningerArmin PasseckerMatthias WyssChristian ScheurerSergio WittlinHans-Peter BeckNicolas M. B. BrancucciTill S. VossNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Eva Hitz Olivia Grüninger Armin Passecker Matthias Wyss Christian Scheurer Sergio Wittlin Hans-Peter Beck Nicolas M. B. Brancucci Till S. Voss The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis
description	Hitz et al. describe the role of the protein kinase PfCK2α in the development of the human malaria parasite Plasmodium falciparum. Using mutant parasites, they show that PfCK2α is not only essential for asexual but also sexual development of P. falciparum blood stage parasites, and hence it may hold promise as a potential target for antimalarial drugs.
format	article
author	Eva Hitz Olivia Grüninger Armin Passecker Matthias Wyss Christian Scheurer Sergio Wittlin Hans-Peter Beck Nicolas M. B. Brancucci Till S. Voss
author_facet	Eva Hitz Olivia Grüninger Armin Passecker Matthias Wyss Christian Scheurer Sergio Wittlin Hans-Peter Beck Nicolas M. B. Brancucci Till S. Voss
author_sort	Eva Hitz
title	The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis
title_short	The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis
title_full	The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis
title_fullStr	The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis
title_full_unstemmed	The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis
title_sort	catalytic subunit of plasmodium falciparum casein kinase 2 is essential for gametocytogenesis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a968a781e2a9433ca72783a35e1bac0a
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The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis

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