Quantification and localization of oncogenic receptor tyrosine kinase variant transcripts using molecular inversion probes
Abstract Oncogenic membrane receptor tyrosine kinases such as MET and EGFR, or auto-active variants thereof, are important targets for cancer precision therapy. Targeted inhibition of these oncogenic receptors however invariably leads to resistance, resulting from acquisition of resistance-inducing...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
|
| Subjects: | |
| Online Access: | https://doaj.org/article/a96e3530439a41b7b9df6a5ba6233936 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|