Crystal structure of an assembly intermediate of respiratory Complex II

The mechanism for covalent flavinylation of flavoenzymes is still unclear. Here, the authors propose a mechanism based on the crystal structure of a flavinylation assembly intermediate of the E. coli respiratory Complex II comprising the E. coli FrdA subunit bound to covalent FAD and crosslinked wit...

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Autores principales:	Pankaj Sharma, Elena Maklashina, Gary Cecchini, T. M. Iverson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a973f3002bed4ac7835c55391dc6a46c
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id	oai:doaj.org-article:a973f3002bed4ac7835c55391dc6a46c
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spelling	oai:doaj.org-article:a973f3002bed4ac7835c55391dc6a46c2021-12-02T15:34:46ZCrystal structure of an assembly intermediate of respiratory Complex II10.1038/s41467-017-02713-82041-1723https://doaj.org/article/a973f3002bed4ac7835c55391dc6a46c2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02713-8https://doaj.org/toc/2041-1723The mechanism for covalent flavinylation of flavoenzymes is still unclear. Here, the authors propose a mechanism based on the crystal structure of a flavinylation assembly intermediate of the E. coli respiratory Complex II comprising the E. coli FrdA subunit bound to covalent FAD and crosslinked with its assembly factor SdhE.Pankaj SharmaElena MaklashinaGary CecchiniT. M. IversonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pankaj Sharma Elena Maklashina Gary Cecchini T. M. Iverson Crystal structure of an assembly intermediate of respiratory Complex II
description	The mechanism for covalent flavinylation of flavoenzymes is still unclear. Here, the authors propose a mechanism based on the crystal structure of a flavinylation assembly intermediate of the E. coli respiratory Complex II comprising the E. coli FrdA subunit bound to covalent FAD and crosslinked with its assembly factor SdhE.
format	article
author	Pankaj Sharma Elena Maklashina Gary Cecchini T. M. Iverson
author_facet	Pankaj Sharma Elena Maklashina Gary Cecchini T. M. Iverson
author_sort	Pankaj Sharma
title	Crystal structure of an assembly intermediate of respiratory Complex II
title_short	Crystal structure of an assembly intermediate of respiratory Complex II
title_full	Crystal structure of an assembly intermediate of respiratory Complex II
title_fullStr	Crystal structure of an assembly intermediate of respiratory Complex II
title_full_unstemmed	Crystal structure of an assembly intermediate of respiratory Complex II
title_sort	crystal structure of an assembly intermediate of respiratory complex ii
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/a973f3002bed4ac7835c55391dc6a46c
work_keys_str_mv	AT pankajsharma crystalstructureofanassemblyintermediateofrespiratorycomplexii AT elenamaklashina crystalstructureofanassemblyintermediateofrespiratorycomplexii AT garycecchini crystalstructureofanassemblyintermediateofrespiratorycomplexii AT tmiverson crystalstructureofanassemblyintermediateofrespiratorycomplexii
_version_	1718386736852107264

Crystal structure of an assembly intermediate of respiratory Complex II

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