Crystal structure of an assembly intermediate of respiratory Complex II
The mechanism for covalent flavinylation of flavoenzymes is still unclear. Here, the authors propose a mechanism based on the crystal structure of a flavinylation assembly intermediate of the E. coli respiratory Complex II comprising the E. coli FrdA subunit bound to covalent FAD and crosslinked wit...
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oai:doaj.org-article:a973f3002bed4ac7835c55391dc6a46c2021-12-02T15:34:46ZCrystal structure of an assembly intermediate of respiratory Complex II10.1038/s41467-017-02713-82041-1723https://doaj.org/article/a973f3002bed4ac7835c55391dc6a46c2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02713-8https://doaj.org/toc/2041-1723The mechanism for covalent flavinylation of flavoenzymes is still unclear. Here, the authors propose a mechanism based on the crystal structure of a flavinylation assembly intermediate of the E. coli respiratory Complex II comprising the E. coli FrdA subunit bound to covalent FAD and crosslinked with its assembly factor SdhE.Pankaj SharmaElena MaklashinaGary CecchiniT. M. IversonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Pankaj Sharma Elena Maklashina Gary Cecchini T. M. Iverson Crystal structure of an assembly intermediate of respiratory Complex II |
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The mechanism for covalent flavinylation of flavoenzymes is still unclear. Here, the authors propose a mechanism based on the crystal structure of a flavinylation assembly intermediate of the E. coli respiratory Complex II comprising the E. coli FrdA subunit bound to covalent FAD and crosslinked with its assembly factor SdhE. |
format |
article |
author |
Pankaj Sharma Elena Maklashina Gary Cecchini T. M. Iverson |
author_facet |
Pankaj Sharma Elena Maklashina Gary Cecchini T. M. Iverson |
author_sort |
Pankaj Sharma |
title |
Crystal structure of an assembly intermediate of respiratory Complex II |
title_short |
Crystal structure of an assembly intermediate of respiratory Complex II |
title_full |
Crystal structure of an assembly intermediate of respiratory Complex II |
title_fullStr |
Crystal structure of an assembly intermediate of respiratory Complex II |
title_full_unstemmed |
Crystal structure of an assembly intermediate of respiratory Complex II |
title_sort |
crystal structure of an assembly intermediate of respiratory complex ii |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/a973f3002bed4ac7835c55391dc6a46c |
work_keys_str_mv |
AT pankajsharma crystalstructureofanassemblyintermediateofrespiratorycomplexii AT elenamaklashina crystalstructureofanassemblyintermediateofrespiratorycomplexii AT garycecchini crystalstructureofanassemblyintermediateofrespiratorycomplexii AT tmiverson crystalstructureofanassemblyintermediateofrespiratorycomplexii |
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1718386736852107264 |