Burden of disease caused by otitis media: systematic review and global estimates.

<h4>Background</h4>Otitis media (OM) is a leading cause of health care visits and drugs prescription. Its complications and sequelae are important causes of preventable hearing loss, particularly in developing countries. Within the Global Burden of Diseases, Injuries, and Risk Factors St...

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Autores principales:	Lorenzo Monasta, Luca Ronfani, Federico Marchetti, Marcella Montico, Liza Vecchi Brumatti, Alessandro Bavcar, Domenico Grasso, Chiara Barbiero, Giorgio Tamburlini
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a980f4b13f7d4ad8977357a247b83585
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spelling	oai:doaj.org-article:a980f4b13f7d4ad8977357a247b835852021-11-18T07:20:10ZBurden of disease caused by otitis media: systematic review and global estimates.1932-620310.1371/journal.pone.0036226https://doaj.org/article/a980f4b13f7d4ad8977357a247b835852012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22558393/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Otitis media (OM) is a leading cause of health care visits and drugs prescription. Its complications and sequelae are important causes of preventable hearing loss, particularly in developing countries. Within the Global Burden of Diseases, Injuries, and Risk Factors Study, for the year 2005 we estimated the incidence of acute OM, chronic suppurative OM, and related hearing loss and mortality for all ages and the 21 WHO regional areas.<h4>Methods</h4>We identified risk factors, complications and sequelae of OM. We carried out an extensive literature review (Medline, Embase, Lilacs and Wholis) which lead to the selection of 114 papers comprising relevant data. Data were available from 15 of the 21 WHO regions. To estimate incidence and prevalence for all countries we adopted a two stage approach based on risk factors formulas and regression modelling.<h4>Results</h4>Acute OM incidence rate is 10.85% i.e. 709 million cases each year with 51% of these occurring in under-fives. Chronic suppurative OM incidence rate is 4.76 ‰ i.e. 31 million cases, with 22.6% of cases occurring annually in under-fives. OM-related hearing impairment has a prevalence of 30.82 per ten-thousand. Each year 21 thousand people die due to complications of OM.<h4>Conclusions</h4>Our study is the first attempt to systematically review the available information and provide global estimates for OM and related conditions. The overall burden deriving from AOM, CSOM and their sequelae is considerable, particularly in the first five years of life and in the poorest countries. The findings call for incorporating OM-focused action within preventive and case management strategies, with emphasis on the more affected.Lorenzo MonastaLuca RonfaniFederico MarchettiMarcella MonticoLiza Vecchi BrumattiAlessandro BavcarDomenico GrassoChiara BarbieroGiorgio TamburliniPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 4, p e36226 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Lorenzo Monasta Luca Ronfani Federico Marchetti Marcella Montico Liza Vecchi Brumatti Alessandro Bavcar Domenico Grasso Chiara Barbiero Giorgio Tamburlini Burden of disease caused by otitis media: systematic review and global estimates.
description	<h4>Background</h4>Otitis media (OM) is a leading cause of health care visits and drugs prescription. Its complications and sequelae are important causes of preventable hearing loss, particularly in developing countries. Within the Global Burden of Diseases, Injuries, and Risk Factors Study, for the year 2005 we estimated the incidence of acute OM, chronic suppurative OM, and related hearing loss and mortality for all ages and the 21 WHO regional areas.<h4>Methods</h4>We identified risk factors, complications and sequelae of OM. We carried out an extensive literature review (Medline, Embase, Lilacs and Wholis) which lead to the selection of 114 papers comprising relevant data. Data were available from 15 of the 21 WHO regions. To estimate incidence and prevalence for all countries we adopted a two stage approach based on risk factors formulas and regression modelling.<h4>Results</h4>Acute OM incidence rate is 10.85% i.e. 709 million cases each year with 51% of these occurring in under-fives. Chronic suppurative OM incidence rate is 4.76 ‰ i.e. 31 million cases, with 22.6% of cases occurring annually in under-fives. OM-related hearing impairment has a prevalence of 30.82 per ten-thousand. Each year 21 thousand people die due to complications of OM.<h4>Conclusions</h4>Our study is the first attempt to systematically review the available information and provide global estimates for OM and related conditions. The overall burden deriving from AOM, CSOM and their sequelae is considerable, particularly in the first five years of life and in the poorest countries. The findings call for incorporating OM-focused action within preventive and case management strategies, with emphasis on the more affected.
format	article
author	Lorenzo Monasta Luca Ronfani Federico Marchetti Marcella Montico Liza Vecchi Brumatti Alessandro Bavcar Domenico Grasso Chiara Barbiero Giorgio Tamburlini
author_facet	Lorenzo Monasta Luca Ronfani Federico Marchetti Marcella Montico Liza Vecchi Brumatti Alessandro Bavcar Domenico Grasso Chiara Barbiero Giorgio Tamburlini
author_sort	Lorenzo Monasta
title	Burden of disease caused by otitis media: systematic review and global estimates.
title_short	Burden of disease caused by otitis media: systematic review and global estimates.
title_full	Burden of disease caused by otitis media: systematic review and global estimates.
title_fullStr	Burden of disease caused by otitis media: systematic review and global estimates.
title_full_unstemmed	Burden of disease caused by otitis media: systematic review and global estimates.
title_sort	burden of disease caused by otitis media: systematic review and global estimates.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/a980f4b13f7d4ad8977357a247b83585
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Burden of disease caused by otitis media: systematic review and global estimates.

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