Systematic Review of Pediatric Functional Gastrointestinal Disorders (Rome IV Criteria)

Functional gastrointestinal disorders (FGID) are common among children and may cause a significant symptom burden. The Rome criteria are symptom-based guidelines for the assessment of FGID among children and adults. The aim of this systematic review was to estimate the prevalence of FGID utilizing t...

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Autores principales:	Angharad Vernon-Roberts, India Alexander, Andrew S. Day
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	prevalence functional GI gut disorders Rome IV Medicine R
Acceso en línea:	https://doaj.org/article/a9877dd9ef094f2e99dc6cba374c20c0
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spelling	oai:doaj.org-article:a9877dd9ef094f2e99dc6cba374c20c02021-11-11T17:42:21ZSystematic Review of Pediatric Functional Gastrointestinal Disorders (Rome IV Criteria)10.3390/jcm102150872077-0383https://doaj.org/article/a9877dd9ef094f2e99dc6cba374c20c02021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/5087https://doaj.org/toc/2077-0383Functional gastrointestinal disorders (FGID) are common among children and may cause a significant symptom burden. The Rome criteria are symptom-based guidelines for the assessment of FGID among children and adults. The aim of this systematic review was to estimate the prevalence of FGID utilizing the revised Rome IV criteria. Nine health databases were searched. The inclusion criteria were: prospective FGID prevalence data using the Rome IV criteria for children up to 18 years, and the exclusion criteria were: cohorts with known gastrointestinal or organic conditions. The data were presented as a percentage of children experiencing at least one FGID, as well as in individual categories. The searches identified 376 papers, with 20 included in the final analysis, providing a pooled cohort of 18,935 children. The median prevalence of FGID for children aged up to four years was 22.2% (range 5.8–40%), and aged four–eighteen years was 21.8% (range 19–40%). The most common FGID for children aged 0–12 months was infant regurgitation, the most common FGID for those aged 13–48 months were functional constipation and cyclic vomiting, and, for those aged over four years, functional constipation, functional dyspepsia, and irritable bowel syndrome. This reported overall incidence of FGID may be used as a benchmark of normative data among the general population and comparative data for those with comorbid disease.Angharad Vernon-RobertsIndia AlexanderAndrew S. DayMDPI AGarticleprevalencefunctional GIgut disordersRome IVMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5087, p 5087 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	prevalence functional GI gut disorders Rome IV Medicine R
spellingShingle	prevalence functional GI gut disorders Rome IV Medicine R Angharad Vernon-Roberts India Alexander Andrew S. Day Systematic Review of Pediatric Functional Gastrointestinal Disorders (Rome IV Criteria)
description	Functional gastrointestinal disorders (FGID) are common among children and may cause a significant symptom burden. The Rome criteria are symptom-based guidelines for the assessment of FGID among children and adults. The aim of this systematic review was to estimate the prevalence of FGID utilizing the revised Rome IV criteria. Nine health databases were searched. The inclusion criteria were: prospective FGID prevalence data using the Rome IV criteria for children up to 18 years, and the exclusion criteria were: cohorts with known gastrointestinal or organic conditions. The data were presented as a percentage of children experiencing at least one FGID, as well as in individual categories. The searches identified 376 papers, with 20 included in the final analysis, providing a pooled cohort of 18,935 children. The median prevalence of FGID for children aged up to four years was 22.2% (range 5.8–40%), and aged four–eighteen years was 21.8% (range 19–40%). The most common FGID for children aged 0–12 months was infant regurgitation, the most common FGID for those aged 13–48 months were functional constipation and cyclic vomiting, and, for those aged over four years, functional constipation, functional dyspepsia, and irritable bowel syndrome. This reported overall incidence of FGID may be used as a benchmark of normative data among the general population and comparative data for those with comorbid disease.
format	article
author	Angharad Vernon-Roberts India Alexander Andrew S. Day
author_facet	Angharad Vernon-Roberts India Alexander Andrew S. Day
author_sort	Angharad Vernon-Roberts
title	Systematic Review of Pediatric Functional Gastrointestinal Disorders (Rome IV Criteria)
title_short	Systematic Review of Pediatric Functional Gastrointestinal Disorders (Rome IV Criteria)
title_full	Systematic Review of Pediatric Functional Gastrointestinal Disorders (Rome IV Criteria)
title_fullStr	Systematic Review of Pediatric Functional Gastrointestinal Disorders (Rome IV Criteria)
title_full_unstemmed	Systematic Review of Pediatric Functional Gastrointestinal Disorders (Rome IV Criteria)
title_sort	systematic review of pediatric functional gastrointestinal disorders (rome iv criteria)
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/a9877dd9ef094f2e99dc6cba374c20c0
work_keys_str_mv	AT angharadvernonroberts systematicreviewofpediatricfunctionalgastrointestinaldisordersromeivcriteria AT indiaalexander systematicreviewofpediatricfunctionalgastrointestinaldisordersromeivcriteria AT andrewsday systematicreviewofpediatricfunctionalgastrointestinaldisordersromeivcriteria
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Systematic Review of Pediatric Functional Gastrointestinal Disorders (Rome IV Criteria)

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