Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens

Designing efficient, rapid and low-cost diagnostic technologies targeting nucleic acids remains a challenge. Here the authors present a disposable silicon-based integrated Point-of-Need transducer produced in a standard wet lab and able to chemically-amplify and detect pathogen-specific sequences of...

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Autores principales: Estefania Nunez-Bajo, Alexander Silva Pinto Collins, Michael Kasimatis, Yasin Cotur, Tarek Asfour, Ugur Tanriverdi, Max Grell, Matti Kaisti, Guglielmo Senesi, Karen Stevenson, Firat Güder
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a98aceb5b7574affba0711cdddc4bbe4
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spelling oai:doaj.org-article:a98aceb5b7574affba0711cdddc4bbe42021-12-02T14:42:13ZDisposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens10.1038/s41467-020-19911-62041-1723https://doaj.org/article/a98aceb5b7574affba0711cdddc4bbe42020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19911-6https://doaj.org/toc/2041-1723Designing efficient, rapid and low-cost diagnostic technologies targeting nucleic acids remains a challenge. Here the authors present a disposable silicon-based integrated Point-of-Need transducer produced in a standard wet lab and able to chemically-amplify and detect pathogen-specific sequences of nucleic acids quantitatively in real-time.Estefania Nunez-BajoAlexander Silva Pinto CollinsMichael KasimatisYasin CoturTarek AsfourUgur TanriverdiMax GrellMatti KaistiGuglielmo SenesiKaren StevensonFirat GüderNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Estefania Nunez-Bajo
Alexander Silva Pinto Collins
Michael Kasimatis
Yasin Cotur
Tarek Asfour
Ugur Tanriverdi
Max Grell
Matti Kaisti
Guglielmo Senesi
Karen Stevenson
Firat Güder
Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens
description Designing efficient, rapid and low-cost diagnostic technologies targeting nucleic acids remains a challenge. Here the authors present a disposable silicon-based integrated Point-of-Need transducer produced in a standard wet lab and able to chemically-amplify and detect pathogen-specific sequences of nucleic acids quantitatively in real-time.
format article
author Estefania Nunez-Bajo
Alexander Silva Pinto Collins
Michael Kasimatis
Yasin Cotur
Tarek Asfour
Ugur Tanriverdi
Max Grell
Matti Kaisti
Guglielmo Senesi
Karen Stevenson
Firat Güder
author_facet Estefania Nunez-Bajo
Alexander Silva Pinto Collins
Michael Kasimatis
Yasin Cotur
Tarek Asfour
Ugur Tanriverdi
Max Grell
Matti Kaisti
Guglielmo Senesi
Karen Stevenson
Firat Güder
author_sort Estefania Nunez-Bajo
title Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens
title_short Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens
title_full Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens
title_fullStr Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens
title_full_unstemmed Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens
title_sort disposable silicon-based all-in-one micro-qpcr for rapid on-site detection of pathogens
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/a98aceb5b7574affba0711cdddc4bbe4
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