Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES
The use of synthetic chromosomes and the recombinase-based SCRaMbLE system could enable rapid strain evolution through massive chromosome rearrangements. Here the authors present ReSCuES, which uses auxotrophic markers to rapidly identify yeast with rearrangements for strain engineering.
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Nature Portfolio
2018
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oai:doaj.org-article:a9907f577d24483dabdd7564338c8e602021-12-02T14:39:08ZIdentifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES10.1038/s41467-017-00806-y2041-1723https://doaj.org/article/a9907f577d24483dabdd7564338c8e602018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00806-yhttps://doaj.org/toc/2041-1723The use of synthetic chromosomes and the recombinase-based SCRaMbLE system could enable rapid strain evolution through massive chromosome rearrangements. Here the authors present ReSCuES, which uses auxotrophic markers to rapidly identify yeast with rearrangements for strain engineering.Zhouqing LuoLihui WangYun WangWeimin ZhangYakun GuoYue ShenLinghuo JiangQingyu WuChong ZhangYizhi CaiJunbiao DaiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
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DOAJ |
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DOAJ |
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EN |
topic |
Science Q |
spellingShingle |
Science Q Zhouqing Luo Lihui Wang Yun Wang Weimin Zhang Yakun Guo Yue Shen Linghuo Jiang Qingyu Wu Chong Zhang Yizhi Cai Junbiao Dai Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES |
description |
The use of synthetic chromosomes and the recombinase-based SCRaMbLE system could enable rapid strain evolution through massive chromosome rearrangements. Here the authors present ReSCuES, which uses auxotrophic markers to rapidly identify yeast with rearrangements for strain engineering. |
format |
article |
author |
Zhouqing Luo Lihui Wang Yun Wang Weimin Zhang Yakun Guo Yue Shen Linghuo Jiang Qingyu Wu Chong Zhang Yizhi Cai Junbiao Dai |
author_facet |
Zhouqing Luo Lihui Wang Yun Wang Weimin Zhang Yakun Guo Yue Shen Linghuo Jiang Qingyu Wu Chong Zhang Yizhi Cai Junbiao Dai |
author_sort |
Zhouqing Luo |
title |
Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES |
title_short |
Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES |
title_full |
Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES |
title_fullStr |
Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES |
title_full_unstemmed |
Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES |
title_sort |
identifying and characterizing scrambled synthetic yeast using rescues |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/a9907f577d24483dabdd7564338c8e60 |
work_keys_str_mv |
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_version_ |
1718390731373019136 |