Scalable and accurate deep learning with electronic health records

Artificial intelligence: Algorithm predicts clinical outcomes for hospital inpatients Artificial intelligence outperforms traditional statistical models at predicting a range of clinical outcomes from a patient’s entire raw electronic health record (EHR). A team led by Alvin Rajkomar and Eyal Oren f...

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Autores principales: Alvin Rajkomar, Eyal Oren, Kai Chen, Andrew M. Dai, Nissan Hajaj, Michaela Hardt, Peter J. Liu, Xiaobing Liu, Jake Marcus, Mimi Sun, Patrik Sundberg, Hector Yee, Kun Zhang, Yi Zhang, Gerardo Flores, Gavin E. Duggan, Jamie Irvine, Quoc Le, Kurt Litsch, Alexander Mossin, Justin Tansuwan, De Wang, James Wexler, Jimbo Wilson, Dana Ludwig, Samuel L. Volchenboum, Katherine Chou, Michael Pearson, Srinivasan Madabushi, Nigam H. Shah, Atul J. Butte, Michael D. Howell, Claire Cui, Greg S. Corrado, Jeffrey Dean
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/a9b3a7cdda6e486cba268a16dc6760b2
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spelling oai:doaj.org-article:a9b3a7cdda6e486cba268a16dc6760b22021-12-02T14:22:07ZScalable and accurate deep learning with electronic health records10.1038/s41746-018-0029-12398-6352https://doaj.org/article/a9b3a7cdda6e486cba268a16dc6760b22018-05-01T00:00:00Zhttps://doi.org/10.1038/s41746-018-0029-1https://doaj.org/toc/2398-6352Artificial intelligence: Algorithm predicts clinical outcomes for hospital inpatients Artificial intelligence outperforms traditional statistical models at predicting a range of clinical outcomes from a patient’s entire raw electronic health record (EHR). A team led by Alvin Rajkomar and Eyal Oren from Google in Mountain View, California, USA, developed a data processing pipeline for transforming EHR files into a standardized format. They then applied deep learning models to data from 216,221 adult patients hospitalized for at least 24 h each at two academic medical centers, and showed that their algorithm could accurately predict risk of mortality, hospital readmission, prolonged hospital stay and discharge diagnosis. In all cases, the method proved more accurate than previously published models. The authors provide a case study to serve as a proof-of-concept of how such an algorithm could be used in routine clinical practice in the future.Alvin RajkomarEyal OrenKai ChenAndrew M. DaiNissan HajajMichaela HardtPeter J. LiuXiaobing LiuJake MarcusMimi SunPatrik SundbergHector YeeKun ZhangYi ZhangGerardo FloresGavin E. DugganJamie IrvineQuoc LeKurt LitschAlexander MossinJustin TansuwanDe WangJames WexlerJimbo WilsonDana LudwigSamuel L. VolchenboumKatherine ChouMichael PearsonSrinivasan MadabushiNigam H. ShahAtul J. ButteMichael D. HowellClaire CuiGreg S. CorradoJeffrey DeanNature PortfolioarticleComputer applications to medicine. Medical informaticsR858-859.7ENnpj Digital Medicine, Vol 1, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Computer applications to medicine. Medical informatics
R858-859.7
spellingShingle Computer applications to medicine. Medical informatics
R858-859.7
Alvin Rajkomar
Eyal Oren
Kai Chen
Andrew M. Dai
Nissan Hajaj
Michaela Hardt
Peter J. Liu
Xiaobing Liu
Jake Marcus
Mimi Sun
Patrik Sundberg
Hector Yee
Kun Zhang
Yi Zhang
Gerardo Flores
Gavin E. Duggan
Jamie Irvine
Quoc Le
Kurt Litsch
Alexander Mossin
Justin Tansuwan
De Wang
James Wexler
Jimbo Wilson
Dana Ludwig
Samuel L. Volchenboum
Katherine Chou
Michael Pearson
Srinivasan Madabushi
Nigam H. Shah
Atul J. Butte
Michael D. Howell
Claire Cui
Greg S. Corrado
Jeffrey Dean
Scalable and accurate deep learning with electronic health records
description Artificial intelligence: Algorithm predicts clinical outcomes for hospital inpatients Artificial intelligence outperforms traditional statistical models at predicting a range of clinical outcomes from a patient’s entire raw electronic health record (EHR). A team led by Alvin Rajkomar and Eyal Oren from Google in Mountain View, California, USA, developed a data processing pipeline for transforming EHR files into a standardized format. They then applied deep learning models to data from 216,221 adult patients hospitalized for at least 24 h each at two academic medical centers, and showed that their algorithm could accurately predict risk of mortality, hospital readmission, prolonged hospital stay and discharge diagnosis. In all cases, the method proved more accurate than previously published models. The authors provide a case study to serve as a proof-of-concept of how such an algorithm could be used in routine clinical practice in the future.
format article
author Alvin Rajkomar
Eyal Oren
Kai Chen
Andrew M. Dai
Nissan Hajaj
Michaela Hardt
Peter J. Liu
Xiaobing Liu
Jake Marcus
Mimi Sun
Patrik Sundberg
Hector Yee
Kun Zhang
Yi Zhang
Gerardo Flores
Gavin E. Duggan
Jamie Irvine
Quoc Le
Kurt Litsch
Alexander Mossin
Justin Tansuwan
De Wang
James Wexler
Jimbo Wilson
Dana Ludwig
Samuel L. Volchenboum
Katherine Chou
Michael Pearson
Srinivasan Madabushi
Nigam H. Shah
Atul J. Butte
Michael D. Howell
Claire Cui
Greg S. Corrado
Jeffrey Dean
author_facet Alvin Rajkomar
Eyal Oren
Kai Chen
Andrew M. Dai
Nissan Hajaj
Michaela Hardt
Peter J. Liu
Xiaobing Liu
Jake Marcus
Mimi Sun
Patrik Sundberg
Hector Yee
Kun Zhang
Yi Zhang
Gerardo Flores
Gavin E. Duggan
Jamie Irvine
Quoc Le
Kurt Litsch
Alexander Mossin
Justin Tansuwan
De Wang
James Wexler
Jimbo Wilson
Dana Ludwig
Samuel L. Volchenboum
Katherine Chou
Michael Pearson
Srinivasan Madabushi
Nigam H. Shah
Atul J. Butte
Michael D. Howell
Claire Cui
Greg S. Corrado
Jeffrey Dean
author_sort Alvin Rajkomar
title Scalable and accurate deep learning with electronic health records
title_short Scalable and accurate deep learning with electronic health records
title_full Scalable and accurate deep learning with electronic health records
title_fullStr Scalable and accurate deep learning with electronic health records
title_full_unstemmed Scalable and accurate deep learning with electronic health records
title_sort scalable and accurate deep learning with electronic health records
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/a9b3a7cdda6e486cba268a16dc6760b2
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