Functional characterization of CDK10 and cyclin M truncated variants causing severe developmental disorders

Abstract Background CDK10 is a poorly known cyclin M (CycM)‐dependent kinase. Loss‐of‐function mutations in the genes encoding CycM or CDK10 cause, respectively, STAR or Al Kaissi syndromes, which present a constellation of malformations and dysfunctions. Most reported mutations abolish gene express...

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Bibliographic Details
Main Authors: Thomas Robert, Anne‐Catherine Dock‐Bregeon, Pierre Colas
Format: article
Language:EN
Published: Wiley 2021
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Online Access:https://doaj.org/article/a9b71a335ec247d798d8c68cdf527e63
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